Smart contact lenses as wearable ophthalmic devices for disease monitoring and health management
The eye contains a complex network of physiological information and biomarkers for
monitoring disease and managing health, and ocular devices can be used to effectively …
monitoring disease and managing health, and ocular devices can be used to effectively …
Glaucomatous damage of the macula
There is a growing body of evidence that early glaucomatous damage involves the macula.
The anatomical basis of this damage can be studied using frequency domain optical …
The anatomical basis of this damage can be studied using frequency domain optical …
Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences
G Tezel - Progress in retinal and eye research, 2006 - Elsevier
Reactive oxygen species (ROS) are generated as by-products of cellular metabolism,
primarily in the mitochondria. Although ROS are essential participants in cell signaling and …
primarily in the mitochondria. Although ROS are essential participants in cell signaling and …
IOP and glaucoma damage: The essential role of optic nerve head and retinal mechanosensors
There are many unanswered questions on the relation of intraocular pressure to glaucoma
development and progression. IOP itself cannot be distilled to a single, unifying value …
development and progression. IOP itself cannot be distilled to a single, unifying value …
Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy
Glaucoma is a complex neurodegenerative disorder that is expected to affect 80 million
people by the end of this decade. Retinal ganglion cells (RGCs) are the most affected cell …
people by the end of this decade. Retinal ganglion cells (RGCs) are the most affected cell …
Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma
Glaucoma is characterized by retinal ganglion cell (RGC) pathology and a progressive loss
of vision. Previous studies suggest RGC death is responsible for vision loss in glaucoma, yet …
of vision. Previous studies suggest RGC death is responsible for vision loss in glaucoma, yet …
Retinal ganglion cell layer thickness and local visual field sensitivity in glaucoma
AS Raza, J Cho, CGV de Moraes, M Wang… - Archives of …, 2011 - jamanetwork.com
Objective To compare loss in sensitivity measured using standard automated perimetry
(SAP) with local retinal ganglion cell layer (RGC) thickness measured using frequency …
(SAP) with local retinal ganglion cell layer (RGC) thickness measured using frequency …
Patterns of retinal ganglion cell damage in neurodegenerative disorders: parvocellular vs magnocellular degeneration in optical coherence tomography studies
C La Morgia, L Di Vito, V Carelli, M Carbonelli - Frontiers in neurology, 2017 - frontiersin.org
Many neurodegenerative disorders, such as Parkinson's disease (PD) and Alzheimer's
disease (AD), are characterized by loss of retinal ganglion cells (RGCs) as part of the …
disease (AD), are characterized by loss of retinal ganglion cells (RGCs) as part of the …
Glaucoma: thinking in new ways—a role for autonomous axonal self-destruction and other compartmentalised processes?
Glaucoma is a common neurodegenerative disease that affects retinal ganglion cells
(RGCs). Substantial effort is being expended to determine how RGCs die in glaucoma. As in …
(RGCs). Substantial effort is being expended to determine how RGCs die in glaucoma. As in …
In vivo retinal nerve fiber layer thickness measured by optical coherence tomography predicts visual recovery after surgery for parachiasmal tumors
HV Danesh-Meyer, T Papchenko… - … & visual science, 2008 - iovs.arvojournals.org
purpose. Restoration of visual function after neurosurgery for parachiasmal tumors is
variable and unpredictable. The current study was conducted to determine whether in vivo …
variable and unpredictable. The current study was conducted to determine whether in vivo …