The field of oncology has witnessed an extraordinary surge in the application of big data and
artificial intelligence (AI). AI development has made multiscale and multimodal data fusion …

Abstract The Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/Cas9
system, a groundbreaking innovation in genetic engineering, has revolutionized our …

Glioblastoma (GBM) is the most prevalent primary brain tumor. Recent research emphasizes
the crucial role of microRNAs (miRs) in GBM pathogenesis, and targeting miRs offers an …

Emerging evidence suggests that cryptic translation beyond the annotated translatome
produces proteins with developmental or physiological functions. However, functions of …

Background Recent studies have highlighted the significant role of the NF-κB signaling
pathway in the initiation and progression of cancer. Furthermore, long noncoding RNAs …

Spinal cord injury (SCI) is a severe injury to the central nervous system, and its treatment is
always a major medical challenge. Proinflammatory cell death is considered an important …

There are lots of gene editing tools for targeting genome sequences. Some are almost
known, and most are a complete mystery and undiscovered. CRISPR/Cas editing tools have …

DARS, encoding for aspartyl-tRNA synthetase, is implicated in the pathogenesis of various
cancers, including renal cell carcinoma, glioblastoma, colon cancer, and gastric cancer. Its …

The advent of targeted therapies has led to tremendous improvements in treatment options
and their outcomes in the field of oncology. Yet, many cancers outsmart precision drugs by …

While it is well known that 98–99% of the human genome does not encode proteins, but are
nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs …