African swine fever control and prevention: an update on vaccine development

AC Urbano, F Ferreira - Emerging microbes & infections, 2022 - Taylor & Francis
African swine fever (ASF) is a lethal and highly contagious viral disease of domestic and
wild pigs, listed as a notifiable disease reported to the World Organization for Animal Health …

Vaccines for African swine fever: An update

H Zhang, S Zhao, H Zhang, Z Qin, H Shan… - Frontiers in …, 2023 - frontiersin.org
African swine fever (ASF) is a fatal infectious disease of swine caused by the African swine
fever virus (ASFV). Currently, the disease is listed as a legally notifiable disease that must be …

Highly lethal genotype I and II recombinant African swine fever viruses detected in pigs

D Zhao, E Sun, L Huang, L Ding, Y Zhu, J Zhang… - Nature …, 2023 - nature.com
African swine fever virus (ASFV) poses a great threat to the global pig industry and food
security. Currently, 24 ASFV genotypes have been reported but it is unclear whether …

Deletion of the A137R gene from the pandemic strain of African swine fever virus attenuates the strain and offers protection against the virulent pandemic virus

DP Gladue, E Ramirez-Medina, E Vuono… - Journal of …, 2021 - Am Soc Microbiol
African swine fever virus (ASFV) is causing a devastating pandemic in domestic and wild
swine within an extended geographical area from Central Europe to East Asia, resulting in …

African swine fever virus E120R protein inhibits interferon beta production by interacting with IRF3 to block its activation

H Liu, Z Zhu, T Feng, Z Ma, Q Xue, P Wu, P Li… - Journal of …, 2021 - Am Soc Microbiol
African swine fever is a devastating disease of swine caused by African swine fever virus
(ASFV). The pathogenesis of the disease remains largely unknown, leaving the spread of …

African swine fever virus bearing an I226R gene deletion elicits robust immunity in pigs to African swine fever

Y Zhang, J Ke, J Zhang, J Yang, H Yue, X Zhou… - Journal of …, 2021 - Am Soc Microbiol
African swine fever (ASF) is a severe hemorrhagic infectious disease in pigs caused by
African swine fever virus (ASFV), leading to devastating economic losses in epidemic …

Recombinant ASF live attenuated virus strains as experimental vaccine candidates

DP Gladue, MV Borca - Viruses, 2022 - mdpi.com
African swine fever (ASF) is causing a pandemic affecting swine in a large geographical
area of the Eastern Hemisphere, from Central Europe to East and Southeast Asia, and …

Evaluation of the deletion of MGF110-5L-6L on swine virulence from the pandemic strain of African swine fever virus and use as a DIVA marker in vaccine candidate …

E Ramirez-Medina, E Vuono, E Silva, A Rai… - Journal of …, 2022 - Am Soc Microbiol
African swine fever virus (ASFV) is responsible for an ongoing pandemic that is affecting
central Europe, Asia, and recently the Dominican Republic, the first report of the disease in …

African swine fever virus HLJ/18 CD2v suppresses type I IFN production and IFN-stimulated genes expression through negatively regulating cGMP-AMP synthase …

L Huang, W Chen, H Liu, M Xue, S Dong… - The Journal of …, 2023 - journals.aai.org
African swine fever is a fatal infectious disease caused by African swine fever virus (ASFV).
The high mortality caused by this infectious disease is a significant challenge to the swine …

Thoughts on African swine fever vaccines

DL Rock - Viruses, 2021 - mdpi.com
African swine fever (ASF) is an acute viral hemorrhagic disease of domestic swine with
mortality rates approaching 100%. Devastating ASF outbreaks and continuing epidemics …