Bone is an alive and dynamic organ that is well-differentiated and originated from
mesenchymal tissues. Bone undergoes continuous remodeling during the lifetime of an …

Lipid nanoparticles (LNPs) are spherical vesicles composed of ionizable lipids that are
neutral at physiological pH. Despite their benefits, unmodified LNP drug delivery systems …

High recurrence and metastasis of triple-negative breast cancer (TNBC) after operation is a
leading cause of breast cancer related death. The pre-metastatic niche (PMN) is an …

Idiopathic pulmonary fibrosis (IPF) is a chronic and diffuse form of interstitial lung disease of
unknown etiology with a fatal outcome. Although various strategies for IPF have been …

Parkinson's disease (PD) is second most common neurodegenerative disorder worldwide.
Although drugs and surgery can relieve the symptoms of PD, these therapies are incapable …

Background Adhesive capsulitis is a common shoulder disorder inducing joint capsule
fibrosis and pain. When combined with rotator cuff tear (RCT), treatments can be more …

Over the last decades, magnificent progress in the field of nanopharmaceuticals mostly with
sizes smaller than 100 nm has led to the development of novel delivery systems and …

Particle size distribution and stability are key attributes for the evaluation of the safety and
efficacy profile of medical nanoparticles (Med-NPs). Measuring particle average size and …

BACKGROUND Astaxanthin (ASTA) is a kind of food‐derived active ingredient (FDAI) with
antioxidant and antidiabetic functions. It is nontoxic but its poor solubility and low …

Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading
cause of cancer related deaths world-wide. Liver transplantation, surgical resection, trans …