Neutralising antibody escape of SARS‐CoV‐2 spike protein: risk assessment for antibody‐based Covid‐19 therapeutics and vaccines

D Focosi, F Maggi - Reviews in medical virology, 2021 - Wiley Online Library
The Spike protein is the target of both antibody‐based therapeutics (convalescent plasma,
polyclonal serum, monoclonal antibodies) and vaccines. Mutations in Spike could affect …

SARS-CoV-2 genomics: An Indian perspective on sequencing viral variants

S Srivastava, S Banu, P Singh, DT Sowpati… - Journal of …, 2021 - Springer
Since its emergence as a pneumonia-like outbreak in the Chinese city of Wuhan in late
2019, the novel coronavirus disease COVID-19 has spread widely to become a global …

[HTML][HTML] Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis

RM Barber, RJD Sorensen, DM Pigott, C Bisignano… - The Lancet, 2022 - thelancet.com
Background Timely, accurate, and comprehensive estimates of SARS-CoV-2 daily infection
rates, cumulative infections, the proportion of the population that has been infected at least …

A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses

A Tauzin, M Nayrac, M Benlarbi, SY Gong, R Gasser… - Cell host & …, 2021 - cell.com
While the standard regimen of the BNT162b2 mRNA vaccine for SARS-CoV-2 includes two
doses administered 3 weeks apart, some public health authorities are spacing these doses …

Structure-function analyses of new SARS-CoV-2 variants B. 1.1. 7, B. 1.351 and B. 1.1. 28.1: clinical, diagnostic, therapeutic and public health implications

J Singh, J Samal, V Kumar, J Sharma, U Agrawal… - Viruses, 2021 - mdpi.com
SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus 2) has accumulated
multiple mutations during its global circulation. Recently, three SARS-CoV-2 lineages, B …

[HTML][HTML] Symptomatic reinfection of SARS‐CoV‐2 with spike protein variant N440K associated with immune escape

PR Rani, M Imran, JV Lakshmi, B Jolly… - Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Dear Editor, A number of cases of reinfections in individuals with SARS‐CoV‐2 have
emerged across the globe. 1, 2 With the emergence of genetic variants associated with …

A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

A Tauzin, M Nayrac, M Benlarbi, SY Gong, R Gasser… - Biorxiv, 2021 - biorxiv.org
The standard dosing of the Pfizer/BioNTech BNT162b2 mRNA vaccine validated in clinical
trials includes two doses administered three weeks apart. While the decision by some public …

Variants of concern responsible for SARS‐CoV‐2 vaccine breakthrough infections from India

UB Singh, M Rophina, R Chaudhry… - Journal of medical …, 2022 - Wiley Online Library
Emerging reports of SARS‐CoV‐2 breakthrough infections entail methodical genomic
surveillance for determining the efficacy of vaccines. This study elaborates genomic analysis …

Importation, circulation, and emergence of variants of SARS-CoV-2 in the South Indian state of Karnataka

C Pattabiraman, P Prasad, AK George… - Wellcome Open …, 2022 - pmc.ncbi.nlm.nih.gov
Background: As the coronavirus disease 2019 (COVID-19) pandemic continues, the
selection of genomic variants of severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] COVID-19 mutations: An overview

M Sarkar, I Madabhavi - World Journal of Methodology, 2024 - pmc.ncbi.nlm.nih.gov
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) belongs to the genus
Beta coronavirus and the family of Coronaviridae. It is a positive-sense, non-segmented …