[HTML][HTML] The exposome and liver disease-how environmental factors affect liver health
R Barouki, M Samson, EB Blanc, M Colombo… - Journal of …, 2023 - Elsevier
Since the initial development of the exposome concept, much effort has been devoted to the
characterisation of the exposome through analytical, epidemiological, and toxicological …
characterisation of the exposome through analytical, epidemiological, and toxicological …
Persistent organic pollutants in foods, their interplay with gut microbiota and resultant toxicity
Abstract Persistent Organic Pollutants (POPs) have become immensely prevalent in the
environment as a result of their unique chemical properties (persistent, semi-volatile and …
environment as a result of their unique chemical properties (persistent, semi-volatile and …
[HTML][HTML] Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet–induced systemic inflammation, microglial activation, and reduced …
The goal of this study was to identify the intrinsic links that explain the effect of a Western diet
(WD) on cognitive dysfunction. Specific pathogen-free, wild-type mice were fed either a …
(WD) on cognitive dysfunction. Specific pathogen-free, wild-type mice were fed either a …
[HTML][HTML] Single-nuclei RNA sequencing assessment of the hepatic effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
Background and Aims Characterization of cell specific transcriptional responses to
hepatotoxicants is lost in the averages of bulk RNA-sequencing (RNA-seq). Single …
hepatotoxicants is lost in the averages of bulk RNA-sequencing (RNA-seq). Single …
Imidacloprid disturbed the gut barrier function and interfered with bile acids metabolism in mice
G Yang, X Yuan, C Jin, D Wang, Y Wang, W Miao… - Environmental …, 2020 - Elsevier
The toxicity of neonicotinoid insecticide imidacloprid (IMI) to mammals has recently received
increasing attention. However, the effects of IMI on the gut barrier and liver function of male …
increasing attention. However, the effects of IMI on the gut barrier and liver function of male …
Gut homeostasis and microbiota under attack: Impact of the different types of food contaminants on gut health
Food contaminants represent food constituents that are accidentally introduced during food
preparation cycle. In addition to their direct toxic effects on human health at different levels …
preparation cycle. In addition to their direct toxic effects on human health at different levels …
Single-cell transcriptomics shows dose-dependent disruption of hepatic zonation by TCDD in mice
Abstract 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) dose-dependently induces the
development of hepatic fat accumulation and inflammation with fibrosis in mice initially in the …
development of hepatic fat accumulation and inflammation with fibrosis in mice initially in the …
Adipose tissue and endocrine-disrupting chemicals: does sex matter?
B Le Magueresse-Battistoni - … of environmental research and public health, 2020 - mdpi.com
Obesity and metabolic-related diseases, among which diabetes, are prominent public health
challenges of the 21st century. It is now well acknowledged that pollutants are a part of the …
challenges of the 21st century. It is now well acknowledged that pollutants are a part of the …
The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value
The aryl hydrocarbon receptor (AhR) is well-known for its major contributions to the cellular
responses against environmental toxins and carcinogens. Notably, AhR has also emerged …
responses against environmental toxins and carcinogens. Notably, AhR has also emerged …
[HTML][HTML] A review of food contaminant 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and its toxicity associated with metabolic disorders
Dioxins are a group of chemicals not only regarded as highly toxic trace environmental
contaminants, but also considered typical contaminants in food. Dioxins spread across the …
contaminants, but also considered typical contaminants in food. Dioxins spread across the …