Monoligated palladium (0) species, L1Pd (0), have emerged as the most active catalytic
species in the cross-coupling cycle. Today, there are methods available to generate the …

Palladium catalysts have become central to modern organic synthesis, particularly in the
context of cross‐coupling reactions to form C− C and C‐heteroatom bonds. The …

Ring walking is an important mechanistic phenomenon leveraged in many catalytic CC
bond forming reactions. However, ring walking has been scarcely studied under Buchwald …

A series of oxidative addition complexes with a general formula (t Bu3P) Pd (Ar) X, as a
class of precatalysts, were synthesized for challenging Suzuki–Miyaura coupling involving …

Kinetic investigations can provide critical mechanistic information for the optimization of the
reaction parameters and reaction development. Modern kinetic analyses such as RPKA and …

Mechanistic studies of the Cu-catalyzed C–N coupling of sterically hindered aryl iodides with
sterically hindered anilines are carried out to shed light on how a recently reported pyrrol-ol …

We report herein a highly efficient Pd-catalyzed amination by “bulky-yet-flexible” Pd-PEPPSI-
IPentAn complexes. The relationship between the N-heterocyclic carbenes (NHCs) structure …

The use of well-defined palladium (II) complexes as precatalysts for C–X cross-coupling
reactions has improved the use of palladium catalysts in organic synthesis including large …

A base-promoted amination of aromatic halides has been developed using a limited amount
of dimethylformamide (DMF) or amine as an amino source. Various aryl halides, including F …

Biaryl phosphorinane ligands derived from addition of biaryl primary phosphines to trans,
trans-dibenzylideneacetone (AlisonPhos and AliPhos) form highly active ligands for Pd …