Cell-based transplantation strategies to promote plasticity following spinal cord injury

CA Ruff, JT Wilcox, MG Fehlings - Experimental neurology, 2012 - Elsevier
Cell transplantation therapy holds potential for repair and functional plasticity following
spinal cord injury (SCI). Stem and progenitor cells are capable of modifying the lesion …

Stem cell-based therapies for spinal cord injury

RS Nandoe Tewarie, A Hurtado… - The journal of spinal …, 2009 - Taylor & Francis
Spinal cord injury (SCI) results in loss of nervous tissue and consequently loss of motor and
sensory function. There is no treatment available that restores the injury-induced loss of …

Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically …

S Karimi-Abdolrezaee, E Eftekharpour… - Journal of …, 2010 - Soc Neuroscience
The transplantation of neural stem/progenitor cells (NPCs) is a promising therapeutic
strategy for spinal cord injury (SCI). However, to date NPC transplantation has exhibited only …

Light-induced rescue of breathing after spinal cord injury

WJ Alilain, X Li, KP Horn, R Dhingra… - Journal of …, 2008 - Soc Neuroscience
Paralysis is a major consequence of spinal cord injury (SCI). After cervical SCI, respiratory
deficits can result through interruption of descending presynaptic inputs to respiratory motor …

Physical rehabilitation as an agent for recovery after spinal cord injury

AL Behrman, SJ Harkema - Physical medicine and rehabilitation clinics of …, 2007 - Elsevier
The initial level of injury and severity of volitional motor and clinically detectable sensory
impairment has been considered the most reliable for predicting neurologic recovery of …

Microfluidics: a new cosset for neurobiology

J Wang, L Ren, L Li, W Liu, J Zhou, W Yu, D Tong… - Lab on a Chip, 2009 - pubs.rsc.org
Recently, microfluidic systems have shown great potential in the study of molecular and
cellular biology. With its excellent properties, such as miniaturization, integration and …

Neural stem cell-based therapies and glioblastoma management: Current evidence and clinical challenges

AY Benmelouka, M Munir, A Sayed, MS Attia… - International journal of …, 2021 - mdpi.com
Gliomas, which account for nearly a quarter of all primary CNS tumors, present significant
contemporary therapeutic challenges, particularly the highest-grade variant (glioblastoma …

Survival of neural stem cell grafts in the lesioned spinal cord is enhanced by a combination of treadmill locomotor training via insulin-like growth factor-1 signaling

DH Hwang, HY Shin, MJ Kwon, JY Choi… - Journal of …, 2014 - Soc Neuroscience
Combining cell transplantation with activity-based rehabilitation is a promising therapeutic
approach for spinal cord repair. The present study was designed to investigate potential …

The crossed phrenic phenomenon and recovery of function following spinal cord injury

HG Goshgarian - Respiratory physiology & neurobiology, 2009 - Elsevier
This review will focus on neural plasticity and recovery of respiratory function after spinal
cord injury and feature the “crossed phrenic phenomenon”(CPP) as a model for …

Stem cells in the adult rat spinal cord: plasticity after injury and treadmill training exercise

A Foret, R Quertainmont, O Botman… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 112, 762–772. Abstract Ependymal cells located around the central
canal of the adult spinal cord are considered as a source of neural stem cells (NSCs) and …