Supplementation with members of the early-life microbiota as" probiotics" is increasingly
used in attempts to beneficially manipulate the preterm infant gut microbiota. We performed …

The sourmash software package uses MinHash-based sketching to create “signatures”,
compressed representations of DNA, RNA, and protein sequences, that can be stored …

As computational biologists continue to be inundated by ever increasing amounts of
metagenomic data, the need for data analysis approaches that keep up with the pace of …

Considerable advances in genomics over the past decade have resulted in vast amounts of
data being generated and deposited in global archives. The growth of these archives …

Alterations in the human microbiome have been observed in a variety of conditions such as
asthma, gingivitis, dermatitis and cancer, and much remains to be learned about the links …

Genome search and/or classification typically involves finding the best-match database
(reference) genomes and has become increasingly challenging due to the growing number …

As the scale of biological data generation has increased, the bottleneck of research has
shifted from data generation to analysis. Researchers commonly need to build …

Mapping metagenome reads to reference databases is the standard approach for assessing
microbial taxonomic and functional diversity from metagenomic data. However, public …

The human gut microbiome is an intricate ecosystem with profound implications for host
metabolism, immune function, and neuroendocrine activity. Over the years, studies have …

The probability Jaccard similarity was recently proposed as a natural generalization of the
Jaccard similarity to measure the proximity of sets whose elements are associated with …