Polyunsaturated fatty acids and their immunomodulatory actions in periodontal disease

J Panezai, T van Dyke - Nutrients, 2023 - mdpi.com
Polyunsaturated fatty acids (PUFAs) are a diverse set of molecules with remarkable
contributions to human physiology. They not only serve as sources of fuel but also cellular …

Genetic polymorphisms in the Interleukins IL1B, IL4, and IL6 are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients

T Cirelli, R Nepomuceno, ACS Rios… - Journal of …, 2020 - Wiley Online Library
Objective To assess whether single nucleotide polymorphisms (SNPs) in the IL10, IL1A,
IL1B, IL4, TNFA, IL6, OPG, RANK, and RANKL genes,“classically” related with periodontitis …

Evidence Linking PPARG Genetic Variants with Periodontitis and Type 2 Diabetes Mellitus in a Brazilian Population

T Cirelli, IG Nicchio, DG Bussaneli, BR Silva… - International Journal of …, 2023 - mdpi.com
The peroxisome proliferator-activated receptor gamma (PPARG) gene encodes a
transcription factor involved in the regulation of complex metabolic and inflammatory …

Calcitriol inhibits osteoclastogenesis in an inflammatory environment by changing the proportion and function of T helper cell subsets (Th2/Th17)

CS Bi, X Li, HL Qu, LJ Sun, Y An, YL Hong… - Cell …, 2020 - Wiley Online Library
Objectives Previously, we found that by regulating T helper (Th) cell polarization, calcitriol
intervention inhibited lipopolysaccharide (LPS)‐induced alveolar bone loss in an animal …

One-year follow-up of the immune profile in serum and selected sites of generalized and localized aggressive periodontitis

ES Martins, JB César-Neto, E Albuquerque-Souza… - Cytokine, 2019 - Elsevier
Background The local and systemic immunological profiles of important inflammatory
mediators in the localized (LAgP) and generalized (GAgP) forms of aggressive periodontitis …

Osteoprotective effect by interleukin-4 (IL-4) on lipoprotein-induced periodontitis

JFL Teixeira, P Henning, FAC Magalhães… - Cytokine, 2023 - Elsevier
Lipoproteins are immunostimulatory bacterial components suggested to participate in
inflammation-induced bone loss in periodontal disease through stimulation of osteoclast …

Functionality of the Interleukin 8 haplotypes in lymphocytes and macrophages in response to gram-negative periodontopathogens

SC Pigossi, G Anovazzi, LS Finoti, MC de Medeiros… - Gene, 2019 - Elsevier
Individuals carrying the ATC/TTC haplotype (Hap-1) in the interleukin 8 (IL8) gene were
reported as more susceptible to chronic periodontitis (CP), an infectious disease associated …

Absolute quantification of Aggregatibacter actinomycetemcomitans in patients carrying haplotypes associated with susceptibility to chronic periodontitis: multifaceted …

T Cirelli, LS Finoti, SCT Corbi, G Anovazzi… - Pathogens and …, 2017 - academic.oup.com
This study aimed to evaluate the association between haplotypes in the interleukin 8 (IL8)
and IL4 genes previously associated to chronic periodontitis (CP) and the levels of …

Characteristics of interleukin-4 gene (C-589T, rs2243250) polymorphism in children with bronchial asthma and allergic rhinitis with isolated or allergic rhinitis-induced …

TY Shumna, OS Fedosieieva, TP Zinchenko… - 2019 - dspace.zsmu.edu.ua
Purpose. To determine the frequency of interleukin-4 (IL-4)(C-589T, rs2243250) single
nucleotide polymorphism in children with bronchial asthma (BA) and allergic rhinitis (AR) …

[PDF][PDF] Investigação da suscetibilidade genética à periodontite crônica associada ao diabetes mellitus tipo 2

T Cirelli - 2020 - repositorio.unesp.br
Periodontite (P) e Diabetes Mellitus Tipo 2 (DM2) são doenças com grande prevalência na
população, e o número de pacientes afetados por ambas as doenças, como comorbidades …