Background Virtual reality (VR) technologies are playing an increasingly important role in
the diagnostics and treatment of mental disorders. Objective To systematically review the …

Adult hippocampal neurogenesis is implicated in antidepressant action, stress responses,
and cognitive functioning. The hippocampus is functionally segregated along its longitudinal …

In recent years, both major depression and antidepressant therapy have been linked to adult
hippocampal neurogenesis. The hippocampus is not a homogeneous brain area, and a …

Medial temporal lobe structures have long been implicated in the pathogenesis of major
depressive disorder. Although findings of smaller hippocampal and amygdalar volumes are …

In order to expand the prospects of developing novel antidepressants for treatment-resistant
populations, animal models should incorporate not only various stress-induced behavioural …

Mood disorders, such as major depressive disorder (MDD), bipolar disorder and
generalized anxiety disorder usually comprise mood related as well as cognitive symptoms …

The hippocampus is crucial for episodic or declarative memory and the theta rhythm has
been implicated in mnemonic processing, but the functional contribution of theta to memory …

Two forms of NMDA receptor (NMDAR)-dependent long-term potentiation (LTP) at
hippocampal CA1 synapses can be distinguished based on their sensitivity to inhibitors of …

Accumulating evidence implicates dysregulation of hippocampal synaptic plasticity in the
pathophysiology of depression. However, the effects of ketamine on synaptic plasticity and …

Remembering autobiographical events can be associated with detailed visual imagery. The
medial temporal lobe (MTL), precuneus and prefrontal cortex are held to jointly enable such …