Spectral characterization of the binding and conformational changes of serum albumins upon interaction with an anticancer drug, anastrozole

R Punith, J Seetharamappa - Spectrochimica Acta Part A: Molecular and …, 2012 - Elsevier
The present study employed different optical spectroscopic techniques viz., fluorescence,
FTIR, circular dichroism (CD) and UV–vis absorption spectroscopy to investigate the …

Insight into the interaction mechanism of HSA with aztreonam: A multispectroscopic and computational approach

AA Sabour, A Khan, MR Alhuzani - Molecules, 2022 - mdpi.com
Aztreonam is a Gram-negative bacteria-targeting synthetic monobactam antibiotic. Human
serum albumin (HSA) plays an important role in the transference of pharmaceuticals …

Tumor selective Ru (III) Schiff bases complexes with strong in vitro activity toward cisplatin-resistant MDA-MB-231 breast cancer cells

M Pavlović, E Kahrović, S Aranđelović… - JBIC Journal of …, 2023 - Springer
Novel ruthenium (III) complexes of general formula Na [RuCl2 (L1− 3-N, O) 2] where L (1–3)
denote deprotonated Schiff bases (HL1-HL3) derived from 5-substituted salicyladehyde and …

Binding interaction and conformational changes of human serum albumin with ranitidine studied by spectroscopic and time-resolved fluorescence methods

MD Meti, ST Nandibewoor, SD Joshi, UA More… - Journal of the Iranian …, 2016 - Springer
This study was designed to examine the interaction of histamine H 2-receptor antagonist
drug ranitidine (RTN) with human serum albumin by multi-spectroscopic methods. The …

Analysis on the interaction and binding properties of daphnoretin and human serum albumin in the presence of cisplatin: multi-spectroscopic methods and docking …

Y Liang, L Xu, H Yang, W Xu, R Hu, X Fan… - European Journal of …, 2021 - Elsevier
The interaction between anticancer drugs and HSA may have a significant impact on the
pharmacology and efficacy of drugs. Drugs change the binding properties of HSA by …

Study on the interaction between isoniazid and bovine serum albumin by fluorescence spectroscopy: the effect of dimethylsulfoxide

SA Markarian, MG Aznauryan - Molecular biology reports, 2012 - Springer
The investigation of the binding between isoniazid (or isonicotinic acid hydrazide, INH) and
serum albumin is of crucial importance to reveal the reason of resistant Mycobacterium …

Binding of an anti-inflammatory drug lornoxicam with blood proteins: insights from spectroscopic investigations

R Punith, AH Hegde, S Jaldappagari - Journal of Fluorescence, 2011 - Springer
The interaction between an anti-inflammatory drug, lornoxicam (LXM) and protein (human
serum albumin and bovine serum albumin) was studied by spectroscopic techniques …

Interactions of oxaliplatin with the cytoplasmic thiol containing ligand glutathione

T Shoeib, BL Sharp - Metallomics, 2012 - academic.oup.com
The complexation of the Pt-based anti-cancer drug oxaliplatin (OxPt) with biological ligands
other than DNA is believed to be a major cellular sink for the drug reducing its therapeutic …

A green chemosensing approach for direct and liquid-liquid extractive spectrophotometric determination of platinum

SH Gaikwad, UB Barache, GS Kamble… - Journal of Analytical …, 2022 - Springer
In this study, a highly selective colorimetric chemosensing behavior of 4-(2'-furalideneimino)-
3-methyl-5-mercapto-1, 2, 4-triazole (FIMMT) was used for the determination of platinum …

Determination of Pt–DNA adducts and the sub-cellular distribution of Pt in human cancer cell lines and the leukocytes of cancer patients, following mono-or …

A Zayed, T Shoeib, SE Taylor, GDD Jones… - International Journal of …, 2011 - Elsevier
This paper describes methodologies, based on sector field inductively-coupled plasma
mass spectrometry (SF-ICP-MS), and their application in the holistic study of the fate of Pt in …