Current developments on the antimalarial, antileishmanial, and antitrypanosomal potential and mechanisms of action of Terminalia spp.

MBT Tali, BP Kamdem, JC Tchouankeu… - South African Journal of …, 2023 - Elsevier
Leishmaniasis, trypanosomiasis, and malaria are three parasitic diseases sharing a similar
demographic and geographical distribution. These infections are intimately related to …

Skimmia anquetilia NP Taylor and Airy Shaw (Rutaceae): A Critical Appriasal of its Ethnobotanical and Pharmacological Activities

M Nabi, N Tabassum, BA Ganai - Frontiers in Plant Science, 2022 - frontiersin.org
Skimmia anquetilia NP Taylor and Airy Shaw (Rutaceae) is a perennial, aromatic,
gregarious wild ornamental shrub native to the Western Himalaya. The plant is used in the …

[PDF][PDF] Bioactive chemical constituents of three crude extracts of Polyalthia Sclerophylla using GC-mass and phytochemical screening and their antibacterial and …

M Mudhafar, I Zainol, HA Alsailawic… - Eurasian Chemical …, 2023 - researchgate.net
Annonaceae famil is considered as the biggest family including more than 130 genus and
about 2300-2500 species [2], and one of these is Polyalthia genus including about 120 …

Unsupervised machine learning, QSAR modelling and web tool development for streamlining the lead identification process of antimalarial flavonoids

JH Zothantluanga, D Chetia, S Rajkhowa… - SAR and QSAR in …, 2023 - Taylor & Francis
Identification of lead compounds with the traditional laboratory approach is expensive and
time-consuming. Nowadays, in silico techniques have emerged as a promising approach for …

Alkaloidal Extracts from Avicennia africana P. Beauv. (Avicenniaceae) Leaf: An Antiplasmodial, Antioxidant, and Erythrocyte Viable

MA Ahmed, EO Ameyaw, FA Armah… - Advances in …, 2024 - Wiley Online Library
Background. The emergence of drug‐resistant parasites impedes disease management and
eradication efforts. Hence, a reinvigorated attempt to search for potent lead compounds in …

[HTML][HTML] Antimicrobial resistance modifying effects and molecular docking studies of Affinine, derived from Tabernaemontana crassa

D Amon, P Manu, E Asante-Kwatia, PK Mante… - Scientific African, 2024 - Elsevier
Tabernaemontana crassa is a native plant indigenous to Ghana which has garnered local
recognition for its purported efficacy against ringworm, wounds, abscesses, and antibacterial …

Anti-malarial evaluation of selected medicinal plants traditionally used for treatment of fever, by inhibition test of heme polymerization

A Salimi, M Hamzeloo-Moghaddam, M Irani… - Annales …, 2024 - Elsevier
Abstract Objectives: World Health Organization (WHO) has reported 249 million cases
infected by malaria worldwide and 608 thousands deaths in 2022. Investigations for new …

Natural Antioxidants as Additional Weapons in the Fight against Malarial Parasite

SA Virendra, C Sahu, A Kumar… - Current Topics in …, 2022 - ingentaconnect.com
Background: All currently available antimalarial drugs are developed from natural product
lineages that may be traced back to herbal medicines, including quinine, lapachol, and …

In vitro and in vivo evaluation of the antimalarial, anti-inflammatory and free radical scavenging potentials of the hydro-alcoholic leaf extract of Microdesmis puberula …

G Adjei-Hinneh, FK Zoiku, E Asante-Kwatia… - Vegetos, 2024 - Springer
Microdesmis puberula (Pandaceae) is an edible shrub noted in traditional medicine for its
antimalarial and anti-inflammatory effects. This study assessed the anti-plasmodial …

Computational screening of phytochemicals for anti-parasitic drug discovery

JH Zothantluanga, AK Umar, H Lalhlenmawia… - … Tools and Databases in …, 2023 - Elsevier
In silico techniques reduce the need for rigorous animal experimentations. It is time-efficient,
eco-friendly, sustainable, and also adheres to the principle of green chemistry. In silico …