Abstract β-Lapachone (β-lap, 1), an ortho-naphthoquinone natural product isolated from the
lapacho tree (Tabebuia avellanedae) in many regions of South America, has received …

Over the past decades, a number of 1, 4‐naphthoquinones have been isolated from natural
resources and several of naphthoquinone derivatives with diverse structural motif have been …

Naphthoquinones are of key importance in organic synthesis and medicinal chemistry. In the
last few years, various synthetic routes have been developed to prepare bioactive …

Naphthoquinones are naturally occurring biologically active entities. Practical de novo
syntheses of three naphthoquinones ie lawsone (1), lapachol (2), and β-lapachone (3b) …

Chalcogen-containing β-lapachone derivatives were synthesized using a straightforward
methodology and evaluated against several cancer cell lines (leukaemia, human colon …

Anticancer active metal complexes with biologically active ligands have the potential to
interact with more than one biological target, which could help to overcome acquired and/or …

Quinones are attractive pharmacological scaffolds for developing new agents for the
treatment of different transmissible and non-transmissible human diseases due to their …

Design and development of drugs in multi-drug resistant (MDR) infections have been of
growing interest. We report the syntheses, and antibacterial and antifungal activities of …

New therapeutic strategies against leishmaniasis are desirable, since the treatment against
disease presents problems, such as the toxicity, high cost and/or parasite resistance. As …

Antibiotic resistant bacteria (ABR) is an alarming issue and it has to be eliminated before
enter into the environment. The role of efflux pump inhibitor, reserpine–a plant alkaloid in …