Metabolomics technology and bioinformatics for precision medicine

RK Azad, V Shulaev - Briefings in bioinformatics, 2019 - academic.oup.com
Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small
group or even individual patients based on their genetics, environment and lifestyle …

Urine metabolomics

A Zhang, H Sun, X Wu, X Wang - Clinica Chimica Acta, 2012 - Elsevier
Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation
of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this …

From Xiaoke to diabetes mellitus: a review of the research progress in traditional Chinese medicine for diabetes mellitus treatment

X Meng, X Liu, J Tan, Q Sheng, D Zhang, B Li… - Chinese medicine, 2023 - Springer
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia
resulting from insulin secretion defects or insulin resistance. The global incidence of DM has …

Power of metabolomics in biomarker discovery and mining mechanisms of obesity

A Zhang, H Sun, X Wang - Obesity Reviews, 2013 - Wiley Online Library
Obesity, the prevalence of which is increasing rapidly worldwide, is recognized as a risk
factor for diabetes, cardiovascular disease, liver disease and renal disease. Unfortunately …

Metabolomics in diabetes

A Zhang, S Qiu, H Xu, H Sun, X Wang - Clinica Chimica Acta, 2014 - Elsevier
Abstract Characterization of metabolic changes is key to early detection, treatment, and
understanding molecular mechanisms of diabetes. Diabetes represents one of the most …

Metabolomics and traditional Chinese medicine

C Hu, G Xu - TrAC Trends in Analytical Chemistry, 2014 - Elsevier
Traditional Chinese medicine (TCM) has attracted increasing interest throughout the world
because of its potential as complementary therapy of choice and a source for discovery of …

Pharmacological tools for the development of traditional Chinese medicine

X Liu, WY Wu, BH Jiang, M Yang, DA Guo - Trends in pharmacological …, 2013 - cell.com
Pharmacology as a modern science was introduced in China approximately 150 years ago,
and has been used since then to study traditional Chinese medicine (TCM). Pharmacology …

Chemometrics applied to quality control and metabolomics for traditional Chinese medicines

S Liu, YZ Liang, H Liu - Journal of chromatography B, 2016 - Elsevier
Abstract Traditional Chinese medicines (TCMs) bring a great challenge in quality control
and evaluating the efficacy because of their complexity of chemical composition …

Holistic lipidomics of the human gut phenotype using validated ultra-high-performance liquid chromatography coupled to hybrid orbitrap mass spectrometry

L Van Meulebroek, E De Paepe, V Vercruysse… - Analytical …, 2017 - ACS Publications
As lipids are assigned a plethora of biological functions, it is evident that dysregulated lipid
metabolism signifies a key element in many pathological conditions. With this rationale, this …

Metabolomics analysis reveals large effect of roughage types on rumen microbial metabolic profile in dairy cows

S Zhao, J Zhao, D Bu, P Sun, J Wang… - Letters in applied …, 2014 - academic.oup.com
The aim of our study was to determine the effect of diets with different types of roughage on
the ruminal microbial metabolite profile in dairy cows. Holstein dairy cows were fed a diet …