A review of recent advances in natural polymer-based scaffolds for musculoskeletal tissue engineering

J Fan, K Abedi-Dorcheh, A Sadat Vaziri… - Polymers, 2022 - mdpi.com
The musculoskeletal (MS) system consists of bone, cartilage, tendon, ligament, and skeletal
muscle, which forms the basic framework of the human body. This system plays a vital role in …

[HTML][HTML] Clinical perspectives for repairing rotator cuff injuries with multi-tissue regenerative approaches

X Zhang, D Wang, Z Wang, SK Ling, PS Yung… - Journal of Orthopaedic …, 2022 - Elsevier
Background In the musculoskeletal system, bone, tendon, and muscle form highly integrated
multi-tissue units such as the rotator cuff complex, which facilitates functional and dynamic …

Growth and differentiation factor-7 immobilized, mechanically strong quadrol-hexamethylene diisocyanate-methacrylic anhydride polyurethane polymer for tendon …

D Wang, X Zhang, KW Ng, Y Rao, C Wang… - Acta Biomaterialia, 2022 - Elsevier
Biological and mechanical cues are both vital for biomaterial aided tendon repair and
regeneration. Here, we fabricated mechanically tendon-like (0 s UV) QHM polyurethane …

A collagen/PLA hybrid scaffold supports tendon‐derived cell growth for tendon repair and regeneration

Y Xie, F Zhang, O Akkus… - Journal of Biomedical …, 2022 - Wiley Online Library
A rotator cuff tendon tear is a common shoulder injury with a relatively high rate of
recurrence after surgical repair. In order to reinforce the repair and reduce the risk of clinical …

Prospective randomized controlled trial for patch augmentation in rotator cuff repair: 24-month outcomes

P Avanzi, L Dei Giudici, A Capone, G Cardoni… - Journal of shoulder and …, 2019 - Elsevier
Background To evaluate the anatomic integrity of rotator cuff repair performed by medialized
single row and augmented by a porcine dermal patch, in comparison with a nonaugmented …

Incorporation of the amniotic membrane as an immunomodulatory design element in collagen scaffolds for tendon repair

RA Hortensius, JH Ebens, MJ Dewey… - … biomaterials science & …, 2018 - ACS Publications
Tendon injuries often require surgical intervention and even then result in poor outcomes
due to scar formation and repeated failure. Biomaterial implants offer the potential to …

[HTML][HTML] A combined physicochemical approach towards human tenocyte phenotype maintenance

CNM Ryan, E Pugliese, N Shologu, D Gaspar… - Materials Today Bio, 2021 - Elsevier
During in vitro culture, bereft of their optimal tissue context, tenocytes lose their phenotype
and function. Considering that tenocytes in their native tissue milieu are exposed …

Plasma-assisted multiscale topographic scaffolds for soft and hard tissue regeneration

W Kim, Y Gwon, YK Kim, S Park, SJ Kang… - NPJ Regenerative …, 2021 - nature.com
The design of transplantable scaffolds for tissue regeneration requires gaining precise
control of topographical properties. Here, we propose a methodology to fabricate …

Surgical repair of large-to-massive rotator cuff tears seems to be a better option than patch augmentation or débridement and biceps tenotomy: a prospective …

C Maillot, E Harly, H Demezon, JC Le Huec - Journal of Shoulder and …, 2018 - Elsevier
Background This prospective study compared the outcomes after 3 different treatments for
large and massive rotator cuff tears. Methods Patients with a diagnosis of large-to-massive …

Characterizing the macro and micro mechanical properties of scaffolds for rotator cuff repair

RDJ Smith, N Zargar, CP Brown, NS Nagra… - Journal of shoulder and …, 2017 - Elsevier
Background Retearing after rotator cuff surgery is a major clinical problem. Numerous
scaffolds are being used to try to reduce retear rates. However, few have demonstrated …