Chronic lung diseases pose a tremendous global burden. At least one in four people suffer
from severe pulmonary sequelae over the course of a lifetime. Despite substantial …

Sepsis-induced acute respiratory distress syndrome (ARDS) has high morbidity and
mortality and arises after lung infection or infection at extrapulmonary sites. An aberrant host …

Background We previously reported that microvesicles (MVs) released by human
mesenchymal stem cells (MSC) were as effective as the cells themselves in both …

Introduction: The acute respiratory distress syndrome (ARDS) is a devastating clinical
condition common in patients with respiratory failure. Based largely on numerous preclinical …

Mesenchymal stromal (stem) cells (MSCs) have multipotent differentiation capacity and exist
in nearly all forms of post-natal organs and tissues. The immunosuppressive and anti …

Human mesenchymal stem cell (MSC) extracellular vesicles (EV) can reduce the severity of
bacterial pneumonia, but little is known about the mechanisms underlying their antimicrobial …

Introduction: Mesenchymal stromal (stem) cell (MSC) therapies are emerging as a promising
therapeutic intervention in patients with Acute Respiratory Distress Syndrome (ARDS) and …

Resolution-phase macrophage population orchestrates active dampening of the
inflammation by secreting anti-inflammatory and proresolving products including interleukin …

Mesenchymal stem cell (MSC) transplantation represents the next breakthrough in the
treatment of currently intractable and devastating neonatal disorders with complex …

Nature has endowed gaseous molecules such as O 2, CO 2, CO, NO, H 2 S, and N 2 with
critical and diverse roles in sustaining life, from supplying energy needed to power life and …