[HTML][HTML] Mannan-Decorated Lipid Calcium Phosphate Nanoparticle Vaccine Increased the Antitumor Immune Response by Modulating the Tumor Microenvironment
L Wu, L Yang, X Qian, W Hu, S Wang… - Journal of Functional …, 2024 - mdpi.com
With the rapid development of tumor immunotherapy, nanoparticle vaccines have attracted
much attention as potential therapeutic strategies. A systematic review and analysis must be …
much attention as potential therapeutic strategies. A systematic review and analysis must be …
Utilizing immunocytokines for cancer therapy
E Runbeck, S Crescioli, SN Karagiannis, S Papa - Antibodies, 2021 - mdpi.com
Cytokine therapy for cancer has indicated efficacy in certain diseases but is generally
accompanied by severe toxicity. The field of antibody–cytokine fusion proteins …
accompanied by severe toxicity. The field of antibody–cytokine fusion proteins …
In Situ Vaccination Following Intratumoral Injection of IL2 and Poly-l-lysine/Iron Oxide/CpG Nanoparticles to a Radiated Tumor Site
Y Zhang, MM Rahman, PA Clark, RN Sriramaneni… - ACS …, 2023 - ACS Publications
The in situ vaccine effect of radiation therapy (RT) has been shown to be limited in both
preclinical and clinical settings, possibly due to the inadequacy of RT alone to stimulate in …
preclinical and clinical settings, possibly due to the inadequacy of RT alone to stimulate in …
[HTML][HTML] Local TLR4 stimulation augments in situ vaccination induced via local radiation and anti-CTLA-4 checkpoint blockade through induction of CD8 T-cell …
JC Jagodinsky, AM Bates, PA Clark… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Radiation therapy (RT) has been demonstrated to generate an in situ
vaccination (ISV) effect in murine models and in patients with cancer; however, this has not …
vaccination (ISV) effect in murine models and in patients with cancer; however, this has not …
Low-Dose Radiation Potentiates the Propagation of Anti-Tumor Immunity against Melanoma Tumor in the Brain after In Situ Vaccination at a Tumor outside the Brain
PA Clark, RN Sriramaneni, AM Bates… - Radiation …, 2021 - meridian.allenpress.com
Brain metastases develop in over 60% of advanced melanoma patients and negatively
impact quality of life and prognosis. In a murine melanoma model, we previously showed …
impact quality of life and prognosis. In a murine melanoma model, we previously showed …
Bridging the gap: unlocking the potential of emerging drug therapies for brain metastasis
J Ding, Y Jiang, N Jiang, S Xing, F Ge, P Ma, Q Tang… - Brain, 2024 - academic.oup.com
Brain metastasis (BrM) remains an unmet clinical need in advanced cancers with an
increasing incidence and poor prognosis. The limited response to various treatments is …
increasing incidence and poor prognosis. The limited response to various treatments is …
Immunotherapy in the context of immune-specialized environment of brain metastases
F James, M Lorger - Discovery Immunology, 2023 - academic.oup.com
Brain metastases (BrM) develop in 20–40% of patients with advanced cancer. They mainly
originate from lung cancer, melanoma, breast cancer, and renal cell carcinoma, and are …
originate from lung cancer, melanoma, breast cancer, and renal cell carcinoma, and are …
Using radiation therapy to prime and propagate an anti-tumor immune response against brain tumors
AJ Onate, PA Clark, ZS Morris - Neuromolecular medicine, 2022 - Springer
Immunotherapies have demonstrated efficacy and survival benefits in some patients
suffering from brain tumors; however, most do not respond and new approaches to enhance …
suffering from brain tumors; however, most do not respond and new approaches to enhance …
A Mannose-Modified Lipid Calcium Phosphate Nanoparticle Vaccine Increased the Anti-Tumor Immune Response by Modulating the Tumor Microenvironment
L Wu, X Qian, W Hu, S Wang, J Yan - 2024 - preprints.org
With the rapid development of tumor immunotherapy, nanoparticle vaccines have attracted
much attention as a potential therapeutic strategy. The potential role of the mannose …
much attention as a potential therapeutic strategy. The potential role of the mannose …
Practice of precision oncology: targeting the tumor immune microenvironment.
WU Siwen, LIU Baorui - Chinese Journal of Cancer …, 2021 - search.ebscohost.com
In recent years, the development of tumor immunotherapy technology has made great
contributions to broadening the field of precision tumor medicine. The immune …
contributions to broadening the field of precision tumor medicine. The immune …