Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and serious
postoperative complication of cardiac surgery requiring cardiopulmonary bypass (CPB), and …

Objectives: The objectives of this review are to discuss the pathophysiology of the pro-
inflammatory response to the cardiopulmonary bypass circuit, the impact of ischemia …

Leukapheresis, the extracorporeal separation of white blood cells (WBCs) from red blood
cells (RBCs) and platelets (PLTs), is a life-saving procedure used for treating patients with …

Background Cardiopulmonary bypass (CPB) is associated with systemic inflammation,
featuring increased levels of circulating pro-inflammatory cytokines. Intra-operative …

Background This study aims to assess the frequency of systemic inflammatory response
syndrome (SIRS) following congenital heart surgery and risk factors associated with this …

This in vitro study evaluated the potential hemostatic effect of fresh frozen plasma (FFP)
ultrafiltration on clotting factors, coagulation parameters, and plasma properties. ABO …

Background. Normothermic machine perfusion (NMP) is used to preserve and test donor
livers before transplantation. During NMP, the liver is metabolically active and produces …

Introduction: Modified ultrafiltration (MUF) is employed at the termination of cardiopulmonary
bypass (CPB) in pediatric and neonatal patients undergoing congenital heart surgery to …

THE INCIDENCE of congenital heart defects is approx-imately 7 to 10 per 1,000 live births. 1
With advancing technology and improved diagnostic, surgical, anesthetic, and postoperative …

Cardiopulmonary bypass perfusion management significantly affects postoperative
outcomes. In recent years, the principles of goal-directed therapy have been applied to the …