Catalyst design within asymmetric organocatalysis

I Iribarren, MR Garcia, C Trujillo - Wiley Interdisciplinary …, 2022 - Wiley Online Library
The field of organocatalysis, more specifically asymmetric organocatalysis, is continuously
expanding having grown significantly over the recent years. However, despite this …

Hydrogen bonding and internal or external Lewis or Brønsted acid assisted (Thio) urea catalysts

MC Gimeno, RP Herrera - European Journal of Organic …, 2020 - Wiley Online Library
The obtainment of more active organocatalysts has promoted the search for new modes of
activation and new organocatalytic systems. Inspired on the mode of activation of enzymes …

Helical oligourea foldamers as powerful hydrogen bonding catalysts for enantioselective C–C bond-forming reactions

D Bécart, V Diemer, A Salaun, M Oiarbide… - Journal of the …, 2017 - ACS Publications
Substantial progress has been made toward the development of metal-free catalysts of
enantioselective transformations, yet the discovery of organic catalysts effective at low …

Using alcohols as simple H 2-equivalents for copper-catalysed transfer semihydrogenations of alkynes

T Kaicharla, BM Zimmermann, M Oestreich… - Chemical …, 2019 - pubs.rsc.org
Copper (I)/N-heterocyclic carbene complexes enable a transfer semihydrogenation of
alkynes employing simple and readily available alcohols such as isopropanol. The practical …

Internal acidity scale and reactivity evaluation of chiral phosphoric acids with different 3, 3′-substituents in Brønsted acid catalysis

K Rothermel, M Melikian, J Hioe, J Greindl… - Chemical …, 2019 - pubs.rsc.org
The concept of hydrogen bonding for enhancing substrate binding and controlling selectivity
and reactivity is central in catalysis. However, the properties of these key hydrogen bonds …

Urea-Based [2] Rotaxanes as Effective Phase-Transfer Organocatalysts: Hydrogen-Bonding Cooperative Activation Enabled by the Mechanical Bond

J Puigcerver, JM Zamora-Gallego… - Journal of the …, 2024 - ACS Publications
We finely designed a set of [2] rotaxanes with urea threads and tested them as hydrogen-
bonding phase-transfer catalysts in two different nucleophilic substitutions requiring the …

A DFT mechanistic study of the organocatalytic asymmetric reaction of aldehydes and homophthalic anhydride

C Trujillo, I Rozas, A Botte, SJ Connon - Chemical Communications, 2017 - pubs.rsc.org
The first DFT study of the cycloaddition of benzaldehyde with homophthalic anhydride under
the influence of a bifunctional organocatalyst is reported. The catalyst first binds and then …

Organo-catalyzed asymmetric cascade annulation reaction for the construction of bi-spirocyclic pyrazolone and oxindole derivatives

BB Sun, JB Chen, JQ Zhang, XP Yang, HP Lv… - Organic Chemistry …, 2020 - pubs.rsc.org
A bifunctional organocatalyst catalyzed tandem annulation reaction between β, γ-
unsaturated α-ketoesters with α-arylidene pyrazolinones was reported. The tandem Michael …

Brønsted–Lewis dual acidic ionic liquid immobilized on mesoporous silica materials as an efficient cooperative catalyst for Mannich reactions

HB Wang, N Yao, L Wang, YL Hu - New Journal of Chemistry, 2017 - pubs.rsc.org
Novel mesoporous silica supported ILs have been prepared and successfully applied as a
heterogeneous catalyst in Mannich reactions. The excellent recyclability of the supported …

Infrared and Raman spectroscopy of non-conventional hydrogen bonding between N, N′-disubstituted urea and thiourea groups: a combined experimental and …

R Le Parc, VT Freitas, P Hermet… - Physical Chemistry …, 2019 - pubs.rsc.org
The variety of H bond (HB) interactions is a source of inspiration for bottom-up molecular
engineering through self-aggregation. Non-conventional intermolecular HBs between N …