Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome
Firre encodes a lncRNA involved in nuclear organization. Here, we show that Firre RNA
expressed from the active X chromosome maintains histone H3K27me3 enrichment on the …
expressed from the active X chromosome maintains histone H3K27me3 enrichment on the …
Testicular mosaicism in non-mosaic postpubertal Klinefelter patients with focal spermatogenesis and in non-mosaic prepubertal Klinefelter boys
S Gül, V Vloeberghs, I Gies, E Goossens - Human Reproduction, 2024 - academic.oup.com
STUDY QUESTION Do testis-specific cells have a normal karyotype in non-mosaic
postpubertal Klinefelter syndrome (KS) patients with focal spermatogenesis and in non …
postpubertal Klinefelter syndrome (KS) patients with focal spermatogenesis and in non …
An epigenetics-based hypothesis of autoantigen development in systemic lupus erythematosus
W Brooks - Epigenomes, 2020 - mdpi.com
Currently, we have a limited understanding of mechanisms leading to systemic lupus
erythematosus, but we know that genetics, environmental factors, and epigenetics contribute …
erythematosus, but we know that genetics, environmental factors, and epigenetics contribute …
Review of the “X chromosome-nucleolus nexus” hypothesis of autoimmune diseases with an update explaining disruption of the nucleolus
WH Brooks - Immunologic Research, 2018 - Springer
The “X chromosome-nucleolus nexus” hypothesis provides a comprehensive explanation of
how autoantibodies can develop following cellular stress. The hypothesis connects …
how autoantibodies can develop following cellular stress. The hypothesis connects …