Maternal Disease With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses

J Hall, NH Adams, L Bartlett, AC Seale… - Clinical infectious …, 2017 - academic.oup.com
Background Infections such as group B Streptococcus (GBS) are an important cause of
maternal sepsis, yet limited data on epidemiology exist. This article, the third of 11, estimates …

Operative vaginal delivery and post-partum infection

O Mohamed-Ahmed, K Hinshaw, M Knight - Best Practice & Research …, 2019 - Elsevier
During the past decade, there has been an increase in the awareness of infections
associated with pregnancy and delivery. The most significant cause of post-partum infection …

Group B Streptococcus circumvents neutrophils and neutrophil extracellular traps during amniotic cavity invasion and preterm labor

E Boldenow, C Gendrin, L Ngo, C Bierle… - Science …, 2016 - science.org
Preterm birth is a leading cause of neonatal morbidity and mortality. Although microbial
invasion of the amniotic cavity (MIAC) is associated with most early preterm births, the …

Systematic review of the clinical development of group B streptococcus serotype-specific capsular polysaccharide-based vaccines

S Dzanibe, SA Madhi - Expert Review of Vaccines, 2018 - Taylor & Francis
Introduction: Vaccination against group BS treptococcus (GBS) during pregnancy could
provide protection against disease in the mother, fetus, and newborn. Immunity through …

Rapid systematic review on risks and outcomes of sepsis: the influence of risk factors associated with health inequalities

S Bladon, D Ashiru-Oredope, N Cunningham… - International Journal for …, 2024 - Springer
Background and aims Sepsis is a serious and life-threatening condition caused by a
dysregulated immune response to an infection. Recent guidance issued in the UK gave …

Group B streptococcal infections in pregnancy and early life

G Manuel, J Twentyman, K Noble… - Clinical Microbiology …, 2024 - journals.asm.org
Bacterial infections with Group B Streptococcus (GBS) are an important cause of adverse
outcomes in pregnant individuals, neonates, and infants. GBS is a common commensal in …

Mast cell chymase decreases the severity of group B Streptococcus infections

C Gendrin, NJ Shubin, E Boldenow, S Merillat… - Journal of Allergy and …, 2018 - Elsevier
Background Group B Streptococcus (GBS) or Streptococcus agalactiae are β-hemolytic
gram-positive bacteria that colonize the lower genital tracts of women and are frequently …

Genetic basis underlying the hyperhemolytic phenotype of Streptococcus agalactiae strain CNCTC10/84

L Zhu, SB Beres, P Yerramilli, L Pruitt… - Journal of …, 2020 - Am Soc Microbiol
Streptococcus agalactiae (group B streptococcus [GBS]) is a major cause of infections in
newborns, pregnant women, and immunocompromised patients. GBS strain CNCTC10/84 is …

Cost-effectiveness analysis of maternal immunisation against group B Streptococcus (GBS) disease: A modelling study

K Giorgakoudi, C O'Sullivan, PT Heath, S Ladhani… - Vaccine, 2018 - Elsevier
Background There is a considerable global burden of invasive group B streptococcal (GBS)
disease. Vaccines are being developed for use in pregnant women to offer protection to …

Functional insights into the high-molecular-mass penicillin-binding proteins of Streptococcus agalactiae revealed by gene deletion and transposon mutagenesis …

L Zhu, P Yerramilli, L Pruitt, A Mishra… - Journal of …, 2021 - Am Soc Microbiol
High-molecular-mass penicillin-binding proteins (PBPs) are enzymes that catalyze the
biosynthesis of bacterial cell wall peptidoglycan. The Gram-positive bacterial pathogen …