Mucosal vaccines, sterilizing immunity, and the future of SARS-CoV-2 virulence

D Focosi, F Maggi, A Casadevall - Viruses, 2022 - mdpi.com
Sterilizing immunity after vaccination is desirable to prevent the spread of infection from
vaccinees, which can be especially dangerous in hospital settings while managing frail …

Systematic review of the safety, immunogenicity, and effectiveness of COVID‐19 vaccines in pregnant and lactating individuals and their infants

W Fu, B Sivajohan, E McClymont… - … of Gynecology & …, 2022 - Wiley Online Library
Background There is significant risk of complications and vulnerability to severe COVID‐19
disease in pregnancy, yet hesitancy exists around COVID‐19 vaccination during pregnancy …

COVID-19 vaccination in pregnant and lactating women: a systematic review

R Falsaperla, G Leone, M Familiari… - Expert Review of …, 2021 - Taylor & Francis
Introduction The concern of undergoing vaccination during pregnancy and lactation, in
absence of data on safety and efficacy in these target populations, is subject of ongoing …

[HTML][HTML] Lack of effects on female fertility and prenatal and postnatal offspring development in rats with BNT162b2, a mRNA-based COVID-19 vaccine

CJ Bowman, M Bouressam, SN Campion… - Reproductive …, 2021 - Elsevier
BNT162b2 is a vaccine developed to prevent coronavirus disease 2019 (COVID-19).
BNT162b2 is a lipid nanoparticle formulated nucleoside-modified messenger RNA (mRNA) …

Codominant IgG and IgA expression with minimal vaccine mRNA in milk of BNT162b2 vaccinees

JM Low, Y Gu, MSF Ng, Z Amin, LY Lee, YPM Ng… - npj Vaccines, 2021 - nature.com
Lactating women can produce protective antibodies in their milk after vaccination, which has
informed antenatal vaccination programs for diseases such as influenza and pertussis …

COVID-19 mRNA vaccine and antibody response in lactating women: a prospective cohort study

N Charepe, J Gonçalves, AM Juliano, DG Lopes… - BMC pregnancy and …, 2021 - Springer
Background Immunological protection via breastfeeding is well known. The immunological
profile of human milk changes during lactation. No clinical trials have been conducted in …

The levels of SARS-CoV-2 specific antibodies in human milk following vaccination

HG Juncker, SJ Mulleners, MJ van Gils… - Journal of Human …, 2021 - journals.sagepub.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are
being administered around the world; however, lactating women were excluded from SARS …

Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine

KJ Kramer, EM Wilfong, K Voss, SM Barone… - Nature …, 2022 - nature.com
RNA-based vaccines against SARS-CoV-2 have proven critical to limiting COVID-19
disease severity and spread. Cellular mechanisms driving antigen-specific responses to …

The effects of COVID-19 vaccination on lactating women: a systematic review of the literature

J Muyldermans, L De Weerdt… - Frontiers in …, 2022 - frontiersin.org
Objectives The availability of new vaccines against COVID-19 urges for guidance about
vaccination during lactation. We aimed to review the literature to get an insight into the …

Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure: a longitudinal study

M Selma-Royo, C Bäuerl, D Mena-Tudela… - Genome medicine, 2022 - Springer
Background Breast milk is a vehicle to transfer protective antibodies from the lactating
mother to the neonate. After SARS-CoV-2 infection, virus-specific IgA and IgG have been …