[HTML][HTML] Development and optimization of vildagliptin solid lipid nanoparticles loaded ocuserts for controlled ocular delivery: A promising approach towards treating …

MMA Elsayed, A Elsayed, MA Fouad… - International Journal of …, 2024 - Elsevier
Diabetes mellitus (DM) is the most prevalent cause of diabetic retinopathy (DRP). DRP has
been recognized for a long time as a microvascular disease. Many drugs were used to treat …

Taste masking and rheology improvement of drug complexed with beta-cyclodextrin and hydroxypropyl-β-cyclodextrin by hot-melt extrusion

LFB Malaquias, LCL Sa-Barreto, DO Freire… - Carbohydrate …, 2018 - Elsevier
This study aimed to mask fluconazole (FLU) taste and improve its rheological properties by
an efficient process of cyclodextrin complexation. For this, hot-melt extrusion (HME) was …

[HTML][HTML] Insight into the inclusion complexation of fluconazole with sulfonatocalix [4] naphthalene in aqueous solution, solid-state, and its antimycotic activity

TA Al Hujran, MK Magharbeh, AY Habashneh… - Molecules, 2022 - mdpi.com
The study aims to assess the interaction between fluconazole and sulfonatocalix [4]
naphthalene towards enhancing its dissolution performance and antimycotic activity. A …

Promising implication of ocuserts in ocular disease

R Thakur, G Swami - Journal of Drug Delivery and Therapeutics, 2012 - jddtonline.info
Ocular route of drug delivery is one of the most interesting and challenging endeavors facing
the pharmaceutical scientist. The anatomy, physiology and biochemistry of the eye render …

[PDF][PDF] Formulation and evaluation of natamycin solid dispersion incorporated ophthalmic films

L Bhandari, AS Patil, U Bolmal, R Masareddy… - Indian J Pharm Educ …, 2022 - ijper.org
Background: The aim of this study was to enhance the solubility of Natamycin, an antifungal
agent used in fungal keratitis, through solid dispersion incorporated ophthalmic films with …

[HTML][HTML] Investigation of hydrogel membranes containing combination of gentamicin and dexamethasone for ocular delivery

P Prabhu, A Dubey, V Parth, V Ghate - International journal of …, 2015 - ncbi.nlm.nih.gov
Background: Hydrogel is a cross-linked network of polymers. Water penetrates these
network causing swelling and giving the hydrogel a soft and rubbery consistency and there …

Novel Phytosomes as Drug Delivery Systems and its Past Decade Trials

AKAE Eltahir, HA Ahad, C Haranath, B Meharajunnisa… - 2023 - indianjournals.com
The present afford is to express phytosomes as a tool for aqueous and non-aqueous drug
permeation. Phytosomes are prepared by conventional dynamic plant constituents like …

[PDF][PDF] Synthesis and physicochemical studies of fluconazole ionic liquids

V Mangrule, Y Pore, J Disouza - Journal of Applied Pharmaceutical …, 2017 - japsonline.com
Active pharmaceutical ingredient (API) based ionic liquids (ILs) were synthesized by
combination of cationic fluconazole (FLC) and anionic ascorbic acid. The solid form of the …

Formulation, Optimization and Evaluation of Ocular Inserts Containing Anti-Fungal Drug.

R Jadhav, V Vaidya, M Mahajan, P Farande… - Journal of Coastal Life …, 2023 - jclmm.com
The goal of the current study was to create Clotrimazole betacyclodextrin ocuserts and
assess the physicochemical aspects of in vitro release and. For improved ocular …

Designing of dexamethasone sodium phosphate ocular films for madras eye: In vitro and in vivo evaluation.

HA Ahad, H Chinthaginjala… - Pakistan Journal of …, 2021 - search.ebscohost.com
The main intention of the current investigation was to fabricate ocular films of
Dexamethasone sodium phosphate (DSP) impregnated in rate controlling membrane and to …