Post-translational modifications (PTMs) are at the heart of many cellular signaling events.
Apart from a single regulatory PTM, there are also PTMs that function in orchestrated …

Owing to rapid growth in the elucidation of genome sequences of various organisms,
deducing proteome sequences has become imperative, in order to have an improved …

Histone post-translational modifications (PTMs) are one of the main mechanisms of
epigenetic regulation. Dysregulation of histone PTMs leads to many human diseases, such …

Cell survival after oxidative DNA damage requires signaling, repair and transcriptional
events often enabled by nucleosome displacement, exchange or removal by chromatin …

Histone posttranslational modifications (PTMs) frequently co-occur on the same chromatin
domains or even in the same molecule. It is now established that these" histone codes" are …

Cervical cancer is the fourth most common female cancer in the world. It is well known that
cervical cancer is closely related to high-risk human papillomavirus (HPV) infection …

The digestion of gluten generates toxic peptides, among which a highly immunogenic
proline-rich 33-mer from wheat α-gliadin, that trigger coeliac disease. Neprosin from the …

Proteases or peptidases are hydrolases that catalyze the breakdown of polypeptide chains
into smaller peptide subunits. Proteases exist in all life forms, including archaea, bacteria …

The ability to map combinatorial patterns of post-translational modifications (PTMs) of
proteins remains challenging for traditional bottom–up mass spectrometry workflows. There …

The analysis of histone post-translational modifications (PTMs) by mass spectrometry (MS)
has been critical to the advancement of the field of epigenetics. The most sensitive and …