Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs
C Wang, H Lin - Genome Biology, 2021 - Springer
PIWI proteins, a subfamily of PAZ/PIWI Domain family RNA-binding proteins, are best known
for their function in silencing transposons and germline development by partnering with …
for their function in silencing transposons and germline development by partnering with …
Elusive inheritance: transgenerational effects and epigenetic inheritance in human environmental disease
Epigenetic mechanisms involving DNA methylation, histone modification, histone variants
and nucleosome positioning, and noncoding RNAs regulate cell-, tissue-, and …
and nucleosome positioning, and noncoding RNAs regulate cell-, tissue-, and …
Jump-starting life: balancing transposable element co-option and genome integrity in the developing mammalian embryo
ME Oomen, ME Torres-Padilla - EMBO reports, 2024 - embopress.org
Remnants of transposable elements (TEs) are widely expressed throughout mammalian
embryo development. Originally infesting our genomes as selfish elements and acting as a …
embryo development. Originally infesting our genomes as selfish elements and acting as a …
MILI, a PIWI family protein, inhibits melanoma cell migration through methylation of LINE1
MILI, a member of the PIWI/AGO gene family, has been well documented to maintain
genome integrity by transposon silencing in animal germ cells. It has been reported to be …
genome integrity by transposon silencing in animal germ cells. It has been reported to be …
Expanding the repertoire of deadenylases
Deadenylases belong to an expanding family of exoribonucleases involved mainly in mRNA
stability and turnover, with the exception of PARN which has additional roles in the …
stability and turnover, with the exception of PARN which has additional roles in the …
PCB153对人肾上皮细胞中LINE-1表达及转座的影响
李佳慈， 景亚青， 茹雅维， 鞠明艳， 李克秋， 李光 - 环境与职业医学, 2018 - jeom.org
目的探究2, 2', 4, 4', 5, 5'-六氯联苯(PCB153) 对人肾上皮细胞系(293T) 细胞中长散在重复序列-
1 (LINE-1) 基因表达和转座的影响. 方法293T 细胞每2 d 传代一次, 传代后立即使用5 μmol/L …
1 (LINE-1) 基因表达和转座的影响. 方法293T 细胞每2 d 传代一次, 传代后立即使用5 μmol/L …
[PDF][PDF] Epigenetic control of cell fate-an interview with Maria-Elena Torres-Padilla
J Chimal-Monroy… - International Journal of …, 2020 - researchgate.net
ABSTRACT Maria-Elena Torres-Padilla's research is focused on how cell fate arises from a
singlecell embryo, the fertilized egg or zygote. After the initial divisions, cell potency …
singlecell embryo, the fertilized egg or zygote. After the initial divisions, cell potency …
λ-integrase mediated seamless vector transgenesis platform
S Roy - 2020 - dr.ntu.edu.sg
Genome engineering is an important component of gene/cell therapy and molecular
medicine. In this respect, several DNA editing tools, such as ZFNs, TALEN and CRISPR-Cas …
medicine. In this respect, several DNA editing tools, such as ZFNs, TALEN and CRISPR-Cas …
[PDF][PDF] WHOLE-GENOME BISULFITE SEQUENCING REVEALS GENOMIC REGIONS VULNERABLE TO EPIGENETIC PERTURBATION
SN Martos - 2017 - jscholarship.library.jhu.edu
Environmental exposures that alter epigenetic marks can have phenotypic consequences
for multiple generations. Prenatal nutrition and environmental stressors have been shown to …
for multiple generations. Prenatal nutrition and environmental stressors have been shown to …
Line1: Implications in the etiology of human diseases, clinical utilities, and pharmacological target for disease treatment
M Khalid - 2017 - search.proquest.com
Long interspersed nuclear elements-1 (Line-1 or L1) accounts for approximately 17% of the
human genome. The majority of L1s are inactive, but∼ 100 remain retrotransposon …
human genome. The majority of L1s are inactive, but∼ 100 remain retrotransposon …