The counterions neutralizing the charges on polyelectrolytes such as DNA or heparin may
dissociate in water and greatly influence the interaction of such polyelectrolytes with …

In this review, we highlight the recent progress in our understanding of the structure,
properties and applications of protein–polyelectrolyte complexes in both bulk and micellar …

Thrombosis and bleeding are common complications of blood-contacting medical device
therapies. In this work, an endothelium membrane mimetic coating (PMPCC/Hep) has been …

Sugar-based osmolyte molecules are known to stabilize proteins under stress, but usually
they have poor chaperone performance in inhibiting protein aggregation. Here, we show …

Protein aggregation is involved in many human diseases, but characterizing the sizes and
shapes of intermediate oligomers (∼ 10–100 nm) that are important to the formation of …

The use of polyelectrolytes to stabilise and deliver polymers relies on a detailed
understanding of their binding, but this can be hard to measure across large numbers of …

Over the past two decades, much information has appeared on electrostatically driven
molecular mechanisms of protein self-assembly and formation of aggregates of different …

The prevention of aggregation during renaturation of urea-denatured carbonic anhydrase B
(CAB) via hydrophobic and Coulomb association with anionic polymers was studied in …

Interactions between proteins and drugs can lead to the formation of stable complexes and
have important implications for several processes related to human health. These …

Complex coacervation was achieved by mixing the lysing enzyme from T. harzianum (LYS)
with polyallylamine hydrochloride (PAH). We show in this work that the study electrostatic …