Considerations for upright particle therapy patient positioning and associated image guidance

L Volz, Y Sheng, M Durante, C Graeff - Frontiers in Oncology, 2022 - frontiersin.org
Particle therapy is a rapidly growing field in cancer therapy. Worldwide, over 100 centers are
in operation, and more are currently in construction phase. The interest in particle therapy is …

Online adaptive planning methods for intensity-modulated radiotherapy

Z Qiu, S Olberg, D den Hertog, A Ajdari… - Physics in Medicine …, 2023 - iopscience.iop.org
Online adaptive radiation therapy aims at adapting a patient's treatment plan to their current
anatomy to account for inter-fraction variations before daily treatment delivery. As this …

[HTML][HTML] A survey of practice patterns for adaptive particle therapy for interfractional changes

P Trnkova, Y Zhang, T Toshito, B Heijmen… - Physics and imaging in …, 2023 - Elsevier
Background and purpose Anatomical changes may compromise the planned target
coverage and organs-at-risk dose in particle therapy. This study reports on the practice …

Management of motion and anatomical variations in charged particle therapy: past, present, and into the future

JM Pakela, A Knopf, L Dong, A Rucinski… - Frontiers in …, 2022 - frontiersin.org
The major aim of radiation therapy is to provide curative or palliative treatment to cancerous
malignancies while minimizing damage to healthy tissues. Charged particle radiotherapy …

[HTML][HTML] Large anatomical changes in head-and-neck cancers–A dosimetric comparison of online and offline adaptive proton therapy

M Bobić, A Lalonde, KP Nesteruk, H Lee… - Clinical and …, 2023 - Elsevier
Purpose This work evaluates an online adaptive (OA) workflow for head-and-neck (H&N)
intensity-modulated proton therapy (IMPT) and compares it with full offline replanning (FOR) …

Evaluating the effect of setup uncertainty reduction and adaptation to geometric changes on normal tissue complication probability using online adaptive head and …

A Lalonde, M Bobić, GC Sharp… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. To evaluate the impact of setup uncertainty reduction (SUR) and adaptation to
geometrical changes (AGC) on normal tissue complication probability (NTCP) when using …

Low-dose computed tomography scanning protocols for online adaptive proton therapy of head-and-neck cancers

KP Nesteruk, M Bobić, GC Sharp, A Lalonde, BA Winey… - Cancers, 2022 - mdpi.com
Simple Summary Adaptive proton therapy requires taking images over the course of
treatment to correct the plan for anatomy changes. Most workflows assume daily imaging for …

A systematic review of volumetric image guidance in proton therapy

M Herrick, S Penfold, A Santos, K Hickson - Physical and Engineering …, 2023 - Springer
In recent years, proton therapy centres have begun to shift from conventional 2D-kV imaging
to volumetric imaging systems for image guided proton therapy (IGPT). This is likely due to …

Optically stimulated luminescence dosimeters for simultaneous measurement of point dose and dose-weighted LET in an adaptive proton therapy workflow

M Bobić, JB Christensen, H Lee, E Choulilitsa… - Frontiers in …, 2024 - frontiersin.org
Purpose To demonstrate the suitability of optically stimulated luminescence detectors
(OSLDs) for accurate simultaneous measurement of the absolute point dose and dose …

Evaluating proton dose and associated range uncertainty using daily cone-beam CT

H Li, WT Hrinivich, H Chen, K Sheikh, MW Ho… - Frontiers in …, 2022 - frontiersin.org
Purpose This study aimed to quantitatively evaluate the range uncertainties that arise from
daily cone-beam CT (CBCT) images for proton dose calculation compared to CT using a …