Learning from nature is a promising approach to achieving specific functions of synthetic
materials. The high material functions, in turn, shed light on the fundamental mechanisms …

At present, surgery is one of the main treatments for bone tumor. However, the risk of
recurrence and the large area of bone defects after surgery pose a great challenge …

Lamellar bone is one of the fundamental structural units of bone tissue and it consists of
mineralised collagen fibrils (MCFs) embedded within an extra-fibrillar matrix comprised of …

At the molecular scale, bone is mainly constituted of type-I collagen, hydroxyapatite, and
water. Different fractions of these constituents compose different composite materials that …

Osteocalcin (Ocn), also known as bone Gla protein, is synthesized by osteoblasts and
thought to regulate energy metabolism, testosterone synthesis and brain development …

Bones are responsible for body support, structure, motion, and several other functions that
enable and facilitate life for many different animal species. They exhibit a complex network …

Protein phosphorylation, critical for cellular regulatory mechanisms, is implicated in various
diseases. However, it remains unknown whether heterogeneity in phosphorylation of key …

Bone is a naturally occurring composite material composed of a stiff mineral phase and a
compliant organic matrix of collagen and non-collagenous proteins (NCP). While diverse …

In addition to thermoelectric (TE) performance tuning through defect or strain engineering,
progress in mechanical research is of increasing importance to wearable applications of …

Osteopontin (OPN) is a one of the most abundant non-collagenous proteins in the bone's
organic matrix. OPN is responsible for mediating bonding at mineral interfaces in the …