Filoviruses are negative-sense single-stranded RNA viruses often associated with severe
and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality …

Next generation sequencing has revealed the presence of numerous RNA viruses in animal
reservoir hosts, including many closely related to known human pathogens. Despite their …

Bats serve as natural hosts of Pteropine orthoreovirus (PRV), an emerging group of bat-
borne, zoonotic viruses. Bats appear to possess unique innate immune system responses …

Evidence suggests that bats are important hosts of filoviruses, yet the specific species
involved remain largely unidentified. Niemann-Pick C1 (NPC1) is an essential entry …

Type I interferon receptor knockout (IFNAR−/−) mice are not able to generate a complete
innate immune response; therefore, these mice are often considered to assess the …

Like other human-pathogenic arenaviruses, Lujo virus (LUJV) is a causative agent of viral
hemorrhagic fever in humans. LUJV infects humans with high mortality rates, but the …

Bats are a natural host for a number of viruses, many of which are zoonotic and thus present
a threat to human health. RNA viruses of the family Filoviridae, many of which cause disease …

Before December 2019 and the COVID-19 pandemic, the general public was to some extent
aware that zoonotic viruses can spill over into the human population and cause a disease …

Next generation sequencing has revealed the presence of many RNA viruses in animal
reservoir hosts, including many closely related to known human pathogens. Despite their …

The Filoviridae family consists of negative-sense, single-stranded, non-segmented RNA
viruses that can cause hemorrhagic diseases in humans and nonhuman primates (NHPs) …