[HTML][HTML] Pathologic function and therapeutic potential of exosomes in cardiovascular disease

S Ailawadi, X Wang, H Gu, GC Fan - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
The heart is a very complex conglomeration of organized interactions between various
different cell types that all aid in facilitating myocardial function through contractility, sufficient …

Wharton's jelly derived mesenchymal stem cells: future of regenerative medicine? Recent findings and clinical significance

I Kalaszczynska, K Ferdyn - BioMed research international, 2015 - Wiley Online Library
Around 5 million annual births in EU and 131 million worldwide give a unique opportunity to
collect lifesaving Wharton's jelly derived mesenchymal stem cells (WJ‐MSC). Evidences that …

[HTML][HTML] Aging alters tissue resident mesenchymal stem cell properties

EU Alt, C Senst, SN Murthy, DP Slakey, CL Dupin… - Stem cell …, 2012 - Elsevier
Tissue resident mesenchymal stem cells (MSCs) are known to participate in tissue
regeneration that follows cell turnover, apoptosis, or necrosis. It has been long known that …

Systematic review of patient factors affecting adipose stem cell viability and function: implications for regenerative therapy

J Varghese, M Griffin, A Mosahebi, P Butler - Stem cell research & therapy, 2017 - Springer
Background The applications for fat grafting have increased recently, within both
regenerative and reconstructive surgery. Although fat harvesting, processing and injection …

Concise review: Adipose-derived stromal vascular fraction cells and stem cells: let's not get lost in translation

JM Gimble, BA Bunnell, ES Chiu, F Guilak - Stem cells, 2011 - academic.oup.com
Subcutaneous fat has emerged as an alternative tissue source for stromal/stem cells in
regenerative medicine. Over the past decade, international research efforts have …

Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells

D Duscher, RC Rennert, M Januszyk, E Anghel… - Scientific reports, 2014 - nature.com
Advanced age is associated with an increased risk of vascular morbidity, attributable in part
to impairments in new blood vessel formation. Mesenchymal stem cells (MSCs) have …

Adipose tissue depots and inflammation: effects on plasticity and resident mesenchymal stem cell function

L Badimon, J Cubedo - Cardiovascular research, 2017 - academic.oup.com
Adipose tissue (AT) is a highly heterogeneous organ. Beside the heterogeneity associated
to different tissue types (white, brown, and 'brite') and its location-related heterogeneity …

Aging adipose: Depot location dictates age-associated expansion and dysfunction

H Von Bank, C Kirsh, J Simcox - Ageing research reviews, 2021 - Elsevier
Adipose tissue has a variety of diverse functions that maintain energy homeostasis. In
conditions of excess energy availability, adipose tissue increases its lipid storage and …

Cellular and molecular mechanisms of vascular injury in diabetes—part I: pathways of vascular disease in diabetes

R Madonna, R De Caterina - Vascular pharmacology, 2011 - Elsevier
Diabetes-induced micro-and macrovascular complications are the major causes of morbidity
and mortality in diabetic patients. While hyperglycemia is a key factor for the pathogenesis of …

Age-induced changes in white, brite, and brown adipose depots: a mini-review

M Schosserer, J Grillari, C Wolfrum, M Scheideler - Gerontology, 2018 - karger.com
Aging is a time-related process of functional decline at organelle, cellular, tissue, and
organismal level that ultimately limits life. Cellular senescence is a state of permanent …