Affatoxins, a group of polyketide-derived furanocoumarins (Fig. 1), are the most toxic and
carcinogenic compounds among the known mycotoxins. Among the at least 16 structurally …

Covering: up to June 2006We review the literature on the enzymes, genes, and whole gene
clusters underlying natural product biosyntheses and their regulation in filamentous fungi …

▪ Abstract Aflatoxins are the most thoroughly studied mycotoxins. Elegant early research on
the biosynthetic scheme of the pathway has allowed a molecular characterization of …

Filamentous fungi have long been used for production of a range of valuable products; with
the advent of molecular biology, it became apparent that these fungi possess considerable …

Enzymology and Molecular Biology of Aflatoxin Biosynthesis | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

It was long been noted that secondary metabolism is associated with fungal development. In
Aspergillus nidulans, conidiation and mycotoxin production are linked by a G protein …

Aflatoxins are highly toxic and carcinogenic substances mainly produced by Aspergillus
flavus and Aspergillus parasiticus. Sterigmatocystin is a penultimate precursor of aflatoxins …

Polyketides (PKs) are a large group of natural products produced by microorganisms and
plants. They are biopolymers of acetate and other short carboxylates and are biosynthesized …

Written by international experts, this book provides a comprehensive picture of the state-of-
the-art in aflatoxin research and control. It considers the worldwide impact of aflatoxins and …

The aflatoxin biosynthetic pathway regulatory gene, aflR, encodes a putative 47-kDa protein
containing a zinc cluster DNA binding motif. It is required for the transcription of all of the …