This review presents evidence from animal and human studies demonstrating the possible
connection and significant impact of poor iron status and psychological distress on …

Anemia affects 36% of pregnant women worldwide. Of those affected, around 40% is due to
iron deficiency (ID). Iron is an essential micronutrient involved in vital processes such as …

The human placenta is a highly specialized organ that is responsible for housing, protecting,
and nourishing the fetus across gestation. The placenta is essential as it functions among …

Background Developmental responses to nutrient deprivation may differ by fetal sex.
Despite this, relationships between maternal prenatal iron biomarkers and birth outcomes …

Iron deficiency, which occurs when iron demands chronically exceed intake, is prevalent in
pregnant women. Iron deficiency during pregnancy poses major risks for the baby, including …

The role of proteostasis and organelle homeostasis dysfunction in human aging and
Alzheimer's disease (AD) remains unclear. Analyzing proteome-wide changes in human …

Background Iron plays a crucial role through various life stages of human. Iron homeostasis
is primarily regulated by iron absorption which is mediated via divalent metal-ion transporter …

Fetal development relies on adequate iron supply by the placenta. The placental
syncytiotrophoblasts (SCTB) express high levels of iron transporters, including ferroportin1 …

Background Murine data suggest that the placenta downregulates ferroportin (FPN) when
iron is limited to prioritize iron for its own needs. Human data on the impact of maternal and …

Pregnancy is a dynamic state involving rapid physiological changes in metabolism, affecting
the health and development of the offspring. During pregnancy, the placenta constitutes a …