Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …

Organs are complex systems composed of different cells, proteins and signalling molecules
that are arranged in a highly ordered structure to orchestrate a myriad of functions in our …

Human lungs are organs with an intricate hierarchical structure and complex composition;
lungs also present heterogeneous mechanical properties that impose dynamic stress on …

Organs-on-chips (OoCs) have attracted significant attention because they can be designed
to mimic in vivo environments. Beyond constructing a single OoC, recent efforts have tried to …

As life expectancy improves and the number of people suffering from various diseases
increases, the need for developing effective personalized disease models is rapidly rising …

Organoids are in vitro cultures of miniature fetal or adult organ-like structures. Their
potentials for use in tissue and organ replacement, disease modeling, toxicology studies …

Drug development is a critical step in the development pipeline of pharmaceutical industry,
commonly performed in traditional cell culture and animal models. Though, those models …

The lungs are affected by illnesses including asthma, chronic obstructive pulmonary
disease, and infections such as influenza and SARS-CoV-2. Physiologically relevant models …

Air quality depends on the various gases and particles present in it. Both natural
phenomena and human activities affect the cleanliness of air. In the last decade, many …

Air pollution consists of highly variable and complex mixtures recognized as major
contributors to morbidity and mortality worldwide. The vast number of chemicals, coupled …