Diazo compounds are versatile organic compounds and have become increasingly
important in organic synthesis and many other fields. In particular, α-diazocarbonyl …

Pyrrolidines are privileged substructures of numerous bioactive natural products and drugs.
How to synthesize these important synthetic targets in a more efficient manner is a hot …

The multicomponent reaction of l-proline, isatins, and excess of methyl propiolates in
methanol unexpectedly afforded 2-(oxoindolin-3-ylidene) propylidene) pyrrolidin-1-yl) …

Reductive cyclization of aryl and vinyl iodides tethered to vinylogous acyl triflates (VATs)
induces a ring-expanding fragmentation to provide cyclic alkynyl ketones, including strained …

Catalytic asymmetric 1, 3-dipolar cycloaddition of azomethine ylides to ethynyl ketones
catalyzed by the Cu (OAc) 2/FOXAP (ferrocenyl oxazolinylphosphine) complex was …

An efficient synthetic strategy for the direct and rapid construction of the [6-5-7] ACD
azatricyclic ring system of numerous calyciphylline A-type alkaloids has been successfully …

A synthesis of the steroidal alkaloid demissidine from epiandrosterone is reported. A ring
fragmentation reaction that efficiently ruptured the D-ring of a diazo ester derivative of …

A convenient [3+ 2] annulation of azomethine ylides with allenoates promoted by
triethylamine produced highly functionalized 2, 5-dihydropyrrole derivatives in moderate to …

A ring fragmentation and intramolecular azomethine ylide 1, 3-dipolar cycloaddition
sequence of reactions was successfully used in the preparation of a known (±)-cycloclavine …

Cyclic γ-oxy-β-hydroxy-α-diazo carbonyls undergo Lewis acid induced ring fragmentation to
provide either ynoates or ynones tethered to an aldehyde, ketone, or ester. The …