Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Native and bioengineered extracellular vesicles for cardiovascular therapeutics

RC de Abreu, H Fernandes… - Nature reviews …, 2020 - nature.com
Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …

Specific anti‐glioma targeted‐delivery strategy of engineered small extracellular vesicles dual‐functionalised by Angiopep‐2 and TAT peptides

Z Zhu, Y Zhai, Y Hao, Q Wang, F Han… - Journal of …, 2022 - Wiley Online Library
Glioma is one of the primary malignant brain tumours in adults, with a poor prognosis.
Pharmacological reagents targeting glioma are limited to achieve the desired therapeutic …

Harnessing the therapeutic potential of extracellular vesicles for biomedical applications using multifunctional magnetic nanomaterials

L Yang, KD Patel, C Rathnam, R Thangam, Y Hou… - Small, 2022 - Wiley Online Library
Extracellular vesicles (eg, exosomes) carrying various biomolecules (eg, proteins, lipids,
and nucleic acids) have rapidly emerged as promising platforms for many biomedical …

Exogenous loading of miRNAs into small extracellular vesicles

RC de Abreu, CV Ramos, C Becher… - Journal of …, 2021 - Wiley Online Library
Small extracellular vesicles (sEVs), through their natural ability to interact with biological
membranes and exploit endogenous processing pathways to convey biological information …

[HTML][HTML] Overcoming the blood-brain barrier: Exosomes as theranostic nanocarriers for precision neuroimaging

C Li, S Qin, Y Wen, W Zhao, Y Huang, J Liu - Journal of Controlled Release, 2022 - Elsevier
Exosomes are cell-derived vesicles with a lipid bilayer membrane that play important roles
in intercellular communication. They provide an unprecedented opportunity for the …

Exosomes and extracellular vesicles as emerging theranostic platforms in cancer research

G Ailuno, S Baldassari, F Lai, T Florio, G Caviglioli - Cells, 2020 - mdpi.com
Exosomes are endosome-derived nanovesicles produced by healthy as well as diseased
cells. Their proteic, lipidic and nucleic acid composition is related to the cell of origin, and by …

Non‐Invasive imaging of extracellular vesicles: Quo vaditis in vivo?

DR Arifin, KW Witwer, JWM Bulte - Journal of Extracellular …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer delimited vesicles released by nearly all cell
types that serve as mediators of intercellular signalling. Recent evidence has shown that …

PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling

AA Khan, F Man, FN Faruqu, J Kim… - Bioconjugate …, 2022 - ACS Publications
Exosomes or small extracellular vesicles (sEVs) are increasingly gaining attention for their
potential as drug delivery systems and biomarkers of disease. Therefore, it is important to …

Goat milk exosomes as natural nanoparticles for detecting inflammatory processes by optical imaging

A Santos‐Coquillat, MI González… - Small, 2022 - Wiley Online Library
Exosomes are cell‐derived nanovesicles with a proven intercellular signaling role in
inflammation processes and immune response. Due to their natural origin and liposome‐like …