Cysteine, a thiol-containing amino acid, is crucial for the synthesis of sulfur-containing
biomolecules that control multiple essential cellular activities. Altered cysteine metabolism …

The human endometrium is a remarkable tissue, undergoing approximately 450 cycles of
proliferation, differentiation, shedding (menstruation), repair and regeneration over a …

The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout
the menstrual cycle in response to ovarian hormones. We have generated dense single-cell …

Deconvolution of regulatory mechanisms that drive transcriptional programs in cancer cells
is key to understanding tumor biology. Herein, we present matched transcriptome (scRNA …

The endometrial lining of the uterus is essential for women's reproductive health and
consists of several different types of epithelial and stromal cells. Although models such as …

Abstract Introduction In the ESGO/ESTRO/ESP guidelines for endometrial carcinoma
management, the risk category of clear cell carcinoma (CCC) is not well defined. In fact …

The endometrium, lining the uterine lumen, is highly essential for human reproduction. Its
exceptional remodeling plasticity, including the transformation process to welcome and nest …

Background Ovarian cancer (OC) is an invasive gynaecologic cancer with a high cancer-
related death rate. The purpose of this study was to establish an invasion-related multigene …

Organoid technology has provided unique insights into human organ development, function,
and diseases. Patient-derived organoids are increasingly used for drug screening, modeling …

The pelviperineal organs of the female reproductive tract form an essential cornerstone of
human procreation. The system comprises the ectodermal external genitalia, the Müllerian …