Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …

The combination of pharmacology and transcranial magnetic stimulation to study the effects
of drugs on TMS-evoked EMG responses (pharmaco-TMS-EMG) has considerably improved …

After a century of false hopes, recent studies have placed the concept of diaschisis at the
centre of the understanding of brain function. Originally, the term 'diaschisis' was coined by …

Understanding how individual neurons integrate the thousands of synaptic inputs they
receive is critical to understanding how the brain works. Modeling studies in silico and …

There is as yet no consensus concerning the neural basis of perception and how it operates
at a mechanistic level. We found that Ca2+ activity in the apical dendrites of a subset of layer …

A basic feature of intelligent systems such as the cerebral cortex is the ability to freely
associate aspects of perceived experience with an internal representation of the world and …

We describe convergent evidence from transcriptomics, morphology, and physiology for a
specialized GABAergic neuron subtype in human cortex. Using unbiased single-nucleus …

Somatostatin-expressing GABAergic neurons constitute a major class of inhibitory neurons
in the mammalian cortex and are characterized by dense wiring into the local network and …

Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

With increasing rates of survival throughout the past several years, stroke remains one of the
leading causes of adult disability. Following the onset of stroke, spontaneous mechanisms of …