The sheer amplitude of biological actions of insulin-like growth factor I (IGF-1) affecting all
type of cells in all tissues suggests a vast signaling landscape for this ubiquitous humoral …

With the progress in neonatal intensive care, there has been an increase in the survival
rates of premature infants. However, this has also led to an increased incidence of neonatal …

Background Sustained systemic inflammatory response (SIR) was associated with poor
postnatal growth in very preterm infants (VPI). We hypothesize that VPI with sustained SIR …

Tissue autofluorescence of fixed tissue sections is a major concern of fluorescence
microscopy. The adrenal cortex emits intense intrinsic fluorescence that interferes with …

The past decades have seen markedly improved survival of increasingly immature preterm
infants, yet major health complications persist. This is particularly true for bronchopulmonary …

Background: Long-term hyperoxia impairs growth of the lungs and contributes to
development of bronchopulmonary dysplasia. Ectodysplasin A (EDA) binds to ectodysplasin …

Bronchopulmonary dysplasia (BPD) is the predominant chronic lung disease in preterm
infants, linked with various adverse long-term outcomes. Multiple prenatal and postnatal risk …

Over the past two decades, interest in the role of the somatotroph growth
hormone/insulinlike growth factor (GH/IGF1) axis in multiple aspects of physiology and …

支气管肺发育不良(bronchopulmonary dysplasia, BPD) 是早产儿严重呼吸系统并发症,
重症病例仍缺乏有效治疗手段. BPD 是多因素疾病, 发病机制主要包括肺泡简单化和肺微血管 …

Oxygen therapy has been one of the main challenges in neonatal intensive care units
(NICU). The guidelines currently in use try to balance the burden of hypoxia and hyperoxia …