Herpes simplex encephalitis results from a series of monogenic primary immunodeficiencies
that impair the TLR3 and UNC-93B-dependent production of IFNα/β and IFNλ in the central …

OBJECTIVE The loss of myenteric neurons in the lower esophageal sphincter (LES)
characterizes achalasia, an esophageal motor disorder. Because the presence of …

This study was designed to test the hypothesis that mononuclear cells in the myenteric
plexus of patients with achalasia may be activated by herpes simplex virus type 1 (HSV-1) …

An enriched environment has previously been described as enhancing natural killer cell
activity of recognizing and killing virally infected cells. However, the effects of environmental …

Herpes simplex virus 1 (HSV1) is best known for causing oral lesions and mild clinical
symptoms, but it can produce a significant range of disease severities and rates of …

ABSTRACT Caveolin-1 (Cav-1), the principal structural protein of caveolae, has been
implicated as a regulator of virus-host interactions. Several viruses exploit caveolae to …

The higher prevalence of cannabis use, abuse or dependence in patients with
schizophrenia, compared with general population is well established. The higher …

The gaseous radical nitric oxide (NO) is generated in the conversion of L-arginine to L-
citrulline by nitric oxide synthases (NOS). Being a highly mobile free radical, NO reacts with …

Intestinal neuropathies have been described in a variety of functional and inflammatory
gastrointestinal disorders. Although the degenerative alterations and neuronal are often …

Abstract Herpes Simplex Virus Type 1 (HSV-1) is an alpha-herpesvirus that primarily causes
oral herpes (cold sores) which tend to recur throughout the lifetime of the patient. However …