Proteinopathy and neuroinflammation are two main hallmarks of neurodegenerative
diseases. They also represent rare common events in an exceptionally broad landscape of …

Chitinases are crucial for the survival of bacterial and fungal pathogens both during host
infection and outside the host in the environment. Chitinases facilitate adhesion onto host …

TDP-43 is the primary or secondary pathological hallmark of neurodegenerative diseases,
such as amyotrophic lateral sclerosis, half of frontotemporal dementia cases, and limbic age …

Amyotrophic lateral sclerosis (ALS) is a fatal motoneuron (MN) disease characterized by
protein misfolding and aggregation leading to cellular degeneration. So far neither …

Essential metals play critical roles in maintaining human health as they participate in various
physiological activities. Nonetheless, both excessive accumulation and deficiency of these …

Abstract Amyotrophic Lateral Sclerosis (ALS) is the most common motor neuron disease, still
incurable. The disease is highly heterogenous both genetically and phenotypically …

Amyotrophic lateral sclerosis is a relentless neurodegenerative disease that is mostly fatal
within 3–5 years and is diagnosed on evidence of progressive upper and lower motor …

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) lie at
opposing ends of a clinical, genetic, and neuropathological continuum. In the last decade, it …

CSF chitinase (Chit-1) and phosphorylated neurofilament heavy chain levels are both raised
in patients with amyotrophic lateral sclerosis (ALS), tweaking interest in these proteins as …

Encephalitis lethargica: clinical features and aetiology Page 1 BRAIN COMMUNICATIONS
https://doi.org/10.1093/braincomms/fcae347 BRAIN COMMUNICATIONS 2024: fcae347 | 1 …