Aquaporin water channels: Roles beyond renal water handling

FH Login, LN Nejsum - Nature Reviews Nephrology, 2023 - nature.com
Aquaporin (AQP) water channels are pivotal to renal water handling and therefore in the
regulation of body water homeostasis. However, beyond the kidney, AQPs facilitate water …

Extracellular vesicles in glioblastoma: Biomarkers and therapeutic tools

I Cela, E Capone, G Trevisi, G Sala - Seminars in Cancer Biology, 2024 - Elsevier
Glioblastoma (GBM) is the most aggressive tumor among the gliomas and intracranial
tumors and to date prognosis for GBM patients remains poor, with a median survival typically …

GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria

L Simone, DL Capobianco, F Di Palma… - Frontiers in Cell and …, 2023 - frontiersin.org
Tunneling nanotubes (TNTs) are long F-actin-positive plasma membrane bridges
connecting distant cells, allowing the intercellular transfer of cellular cargoes, and are found …

[HTML][HTML] The Functional Interaction of KATP and BK Channels with Aquaporin-4 in the U87 Glioblastoma Cell

F Maqoud, L Simone, D Tricarico, GM Camerino… - Biomedicines, 2024 - mdpi.com
K+ channels do play a role in cell shape changes observed during cell proliferation and
apoptosis. Research suggested that the dynamics of the aggregation of Aquaporin-4 (AQP4) …

Iron gallic acid biomimetic nanoparticles for targeted magnetic resonance imaging

Y Chen, Z Zhang, Z Chen, S Jiang, A Reheman… - Plos one, 2024 - journals.plos.org
Developing T1-weighted magnetic resonance imaging (MRI) contrast agents with enhanced
biocompatibility and targeting capabilities is crucial owing to concerns over current agents' …

Aquaporin-4 As A New Potential Molecular Biomarker for Prognosis of Low-Grade Glioma: Comprehensive Analysis Based on Online Platforms

J Zhu, L Shi, Y Su - World Neurosurgery, 2023 - Elsevier
Objective Aquaporin-4 (AQP4) is a significant factor in transcellular and transepithelial water
movement, and abnormal expression of AQP4 has been detected in many types of tumors …

Aquaporin-4 expression levels and mis-localization are inversely linked to peritumoral edema in gliomas of varying aggressiveness

O Valente, P Abbrescia, G Signorile, R Messina… - bioRxiv, 2024 - biorxiv.org
Aquaporin-4 (AQP4) and its extended isoform, AQP4ex, are crucial for regulating brain water
homeostasis. Mis-localization of these isoforms is implicated in various brain tumors …