[PDF][PDF] Cell culture media: a review

M Arora - Mater methods, 2013 - researchgate.net
Types of Cell Culture Media Animal cells can be cultured either using a completely natural
medium or an artificial/synthetic medium along with some natural products. Natural Media …

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

J Scekic‐Zahirovic, O Sendscheid, H El Oussini… - The EMBO …, 2016 - embopress.org
FUS is an RNA‐binding protein involved in amyotrophic lateral sclerosis (ALS) and
frontotemporal dementia (FTD). Cytoplasmic FUS‐containing aggregates are often …

[HTML][HTML] A genome-wide test of the differential susceptibility hypothesis reveals a genetic predictor of differential response to psychological treatments for child anxiety …

R Keers, JRI Coleman, KJ Lester, S Roberts… - Psychotherapy and …, 2016 - karger.com
Background: The differential susceptibly hypothesis suggests that certain genetic variants
moderate the effects of both negative and positive environments on mental health and may …

From global phosphoproteomics to individual proteins: the case of translation elongation factor eEF1A

B Negrutskii, D Vlasenko, A El'skaya - Expert Review of …, 2012 - Taylor & Francis
Phosphoproteomics is often aimed at deciphering the modified components of signaling
pathways in certain organisms, tissues and pathologies. Phosphorylation of housekeeping …

[HTML][HTML] Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention

X Wang, M Han, S Wang, Y Sun, W Zhao, Z Xue… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Splicing factors are essential for nascent pre-mRNA processing and critical in
cancer progression, suggesting that proteins with splicing functions represent potential …

Adipose tissue-derived neurotrophic factor 3 regulates sympathetic innervation and thermogenesis in adipose tissue

X Cui, J Jing, R Wu, Q Cao, F Li, K Li, S Wang… - Nature …, 2021 - nature.com
Activation of brown fat thermogenesis increases energy expenditure and alleviates obesity.
Sympathetic nervous system (SNS) is important in brown/beige adipocyte thermogenesis …

Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma

LK Smith, T Parmenter, M Kleinschmidt… - Nature …, 2022 - nature.com
Despite the success of therapies targeting oncogenes in cancer, clinical outcomes are
limited by residual disease that ultimately results in relapse. This residual disease is often …

Extracellular vesicles derived from ascitic fluid enhance growth and migration of ovarian cancer cells

A Mitra, K Yoshida-Court, TN Solley, M Mikkelson… - Scientific reports, 2021 - nature.com
Ovarian cancer is associated with a high mortality rate due to diagnosis at advanced stages.
Dissemination often occurs intraperitoneally within the ascites fluid. The microenvironment …

UHMK 1 promotes gastric cancer progression through reprogramming nucleotide metabolism

X Feng, D Ma, J Zhao, Y Song, Y Zhu, Q Zhou… - The EMBO …, 2020 - embopress.org
UHMK 1 is a nuclear serine/threonine kinase recently implicated in carcinogenesis.
However, the functions and action mechanisms of UHMK 1 in the pathogenesis of human …

[HTML][HTML] Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

J Canet-Pons, NE Sen, A Arsović… - Neurobiology of …, 2021 - Elsevier
Large polyglutamine expansions in Ataxin-2 (ATXN2) cause multi-system nervous atrophy in
Spinocerebellar Ataxia type 2 (SCA2). Intermediate size expansions carry a risk for selective …