Deubiquitinating enzymes (DUBs), capable of removing ubiquitin (Ub) from protein
substrates, are involved in numerous biological processes. The ubiquitin C-terminal …

Ubiquitin C‑terminal hydrolase‑L1 (UCH‑L1), a member of the lesser‑known
deubiquitinating enzyme family, has deubiquitinase and ubiquitin (Ub) ligase activity and the …

De-ubiquitinating enzymes (DUBs) can reverse the modifications catalyzed by ubiquitin
ligases and as such are believed to be important regulators of a variety of cellular …

The Epstein–Barr virus (EBV) transforms resting B cells and is involved in the development
of B cell lymphomas. We report here that the viral noncoding RNA EBER2 accelerates B cell …

Ubiquitin C-terminal hydrolse-L1 (UCH-L1) is a deubiquitinating enzyme (DUB) that cleaves
the ubiquitin (ub) moiety from ub precursors or protein substrates. The correlation between …

B cells undergo epigenetic remodeling as they differentiate into Ab-secreting cells (ASC).
LSD1 is a histone demethylase known to decommission active enhancers and cooperate …

Microtubules are essential components of the cytoskeleton and are involved in many
aspects of cell responses including cell division, migration, and intracellular signal …

This study explored the role of ubiquitin C-terminal hydrolase-L1 (UCH-L1) in the production
of ROS and tumor invasion. UCH-L1 was found to increase cellular ROS levels and promote …

Normally ubiquitin C-terminal hydrolase L1 (UCH-L1) is expressed in the central nervous
and reproductive systems of adults, but its de novo expression has been detected in many …

Deubiquitinating enzymes (DUBs) have been increasingly implicated in regulation of
cellular processes, but a functional role for Ubiquitin C-terminal Hydrolases (UCHs), which …