Astrocytes are the main support cells of the central nervous system. They also participate in
neuroimmune reactions. In response to pathological and immune stimuli, astrocytes …

Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription (Tat) is a potent
mediator involved in the development of HIV-1-associated neurocognitive disorders …

Abstract Human Immunodeficiency Virus (HIV) is a progressive infection that targets the
immune system, affecting more than 37 million people around the world. While …

Neurological diseases are multifactorial, devastating diseases that are causative for various
neurodegenerative disorders. Emerging evidence points that accumulation of unfolded …

The “shock and kill” HIV‐1 cure strategy proposes eradication of stable cellular reservoirs by
clinical treatment with latency‐reversing agents (LRAs). Although resting CD4+ T cells …

Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND)
comprise a group of illnesses marked by memory and behavioral dysfunction that can occur …

Mortalin is a chaperone protein that regulates physiological functions of cells. Its
multifactorial role allows cells to survive pathological conditions. Pharmacological, chemical …

HIV associated neurocognitive disorders (HAND) are the spectrum of cognitive impairments
present in patients infected with human immunodeficiency virus type 1 (HIV-1). The number …

HIV infection of astrocytes leads to restricted gene expression and replication but abundant
expression of HIV early genes Tat, Nef and Rev. A great deal of neuroHIV research has so …

Though alcoholic liver injury plays the primary role in direct alcohol-related morbidity,
alcohol consumption is also interlinked with many other diseases in extra-hepatic …