Cortical HCN channels: function, trafficking and plasticity
MM Shah - The Journal of physiology, 2014 - Wiley Online Library
The hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels belong to the
superfamily of voltage‐gated potassium ion channels. They are, however, activated by …
superfamily of voltage‐gated potassium ion channels. They are, however, activated by …
HCN channels in behavior and neurological disease: too hyper or not active enough?
AS Lewis, DM Chetkovich - Molecular and Cellular Neuroscience, 2011 - Elsevier
The roles of cells within the nervous system are based on their properties of excitability,
which are in part governed by voltage-gated ion channels. HCN channels underlie the …
which are in part governed by voltage-gated ion channels. HCN channels underlie the …
[HTML][HTML] Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis
Hyperpolarization-activated cation nonselective 1 (HCN1) plasticity in entorhinal cortical
(EC) and hippocampal pyramidal cell dendrites is a salient feature of temporal lobe …
(EC) and hippocampal pyramidal cell dendrites is a salient feature of temporal lobe …
Calcium store depletion induces persistent perisomatic increases in the functional density of h channels in hippocampal pyramidal neurons
R Narayanan, KJ Dougherty, D Johnston - Neuron, 2010 - cell.com
The regulation of intracellular calcium by the endoplasmic reticulum (ER) plays a critical role
in neuronal function. While the consequences associated with depleting calcium from the …
in neuronal function. While the consequences associated with depleting calcium from the …
TRIP8b splice forms act in concert to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons
R Piskorowski, B Santoro, SA Siegelbaum - Neuron, 2011 - cell.com
HCN1 channel subunits, which contribute to the hyperpolarization-activated cation current
(Ih), are selectively targeted to distal apical dendrites of hippocampal CA1 pyramidal …
(Ih), are selectively targeted to distal apical dendrites of hippocampal CA1 pyramidal …