Classical dendritic cells (cDCs) form a critical interface between innate and adaptive
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …

Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …

Dendritic cells (DCs) are instrumental in the initiation of T cell responses, but how thymic
and peripheral tolerogenic DCs differ globally from Toll-like receptor (TLR)-induced …

Lineage-committed αβ and γδ T cells are thought to originate from common intrathymic
multipotent progenitors following instructive T cell receptor (TCR) signals. A subset of lymph …

The cross-talk between thymocytes and thymic stromal cells is fundamental for T cell
development. In humans, intrathymic development of dendritic cells (DCs) is evident but its …

Dendritic cells (DCs) are a heterogeneous group of mononuclear phagocytes with versatile
roles in immunity. They are classified predominantly based on phenotypic and functional …

Cross-presentation by dendritic cells (DCs) of exogenous antigens on MHC class I is
important for the generation of immune responses to intracellular pathogens, as well as for …

Dendritic cells (DCs) play a significant role in establishing self-tolerance through their ability
to present self-antigens to developing T cells in the thymus. DCs are predominantly …

A key unsolved question regarding the developmental origin of conventional and
plasmacytoid dendritic cells (cDCs and pDCs, respectively) resident in the steady-state …

In this review, we described the structure and organization of antigen-recognizing
repertoires of B and T cells from the standpoint of modern immunology. We summarized the …