Strategies to improve the efficiency of somatic cell nuclear transfer

K Srirattana, M Kaneda, R Parnpai - International Journal of Molecular …, 2022 - mdpi.com
Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …

Efficacy of the porcine species in biomedical research

K Gutierrez, N Dicks, WG Glanzner, LB Agellon… - Frontiers in …, 2015 - frontiersin.org
Since domestication, pigs have been used extensively in agriculture and kept as companion
animals. More recently they have been used in biomedical research, given they share many …

A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigs

IC Cho, HB Park, JS Ahn, SH Han, JB Lee, HT Lim… - PLoS …, 2019 - journals.plos.org
Muscle development and lipid accumulation in muscle critically affect meat quality of
livestock. However, the genetic factors underlying myofiber-type specification and …

The Molecular Quality and Mitochondrial Activity of Porcine Cumulus–Oocyte Complexes Are Affected by Their Exposure to Three Endocrine-Active Compounds …

G Gorczyca, K Wartalski, M Romek, M Samiec… - International Journal of …, 2022 - mdpi.com
Thus far, the potential short-and long-term detrimental effects of a variety of environmental
chemicals designated as endocrine-active compounds (EACs) have been found to interfere …

Transmission of dysfunctional mitochondrial DNA and its implications for mammalian reproduction

K Srirattana, JC St. John - Cellular and Molecular Basis of Mitochondrial …, 2019 - Springer
Mitochondrial DNA (mtDNA) encodes proteins for the electron transport chain which
produces the vast majority of cellular energy. MtDNA has its own replication and …

Mitochondrial heteroplasmy in vertebrates using ChIP-sequencing data

T Rensch, D Villar, J Horvath, DT Odom, P Flicek - Genome biology, 2016 - Springer
Background Mitochondrial heteroplasmy, the presence of more than one mitochondrial DNA
(mtDNA) variant in a cell or individual, is not as uncommon as previously thought. It is mostly …

The cyclin-dependent kinase inhibitor, JNJ-7706621, improves in vitro developmental competence of porcine parthenogenetic activation and somatic cell nuclear …

Q Guo, L Jin, HY Zhu, XX Xing, MF Xuan… - Reproduction …, 2018 - CSIRO Publishing
In this study we examined the effects of JNJ-7706621, a cyclin-dependent kinase inhibitor,
on the in vitro growth of pig embryos that had been produced either by parthenogenetic …

Survival of skin graft between transgenic cloned dogs and non-transgenic cloned dogs

GA Kim, HJ Oh, MJ Kim, YK Jo, J Choi, JE Park… - Plos one, 2014 - journals.plos.org
Whereas it has been assumed that genetically modified tissues or cells derived from somatic
cell nuclear transfer (SCNT) should be accepted by a host of the same species, their …

[HTML][HTML] JNJ-7706621

Q Guo, L Jin, HY Zhu, XX Xing, MF Xuan, QR Luo… - srt2104activator.com
In this study we examined the effects of JNJ-7706621, a cyclin-dependent kinase inhibitor,
on the in vitro growth of pig embryos that had been produced either by parthenogenetic …