Vector biology meets disease control: using basic research to fight vector-borne diseases

WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

Mosquito innate immunity

A Kumar, P Srivastava, P Sirisena, SK Dubey, R Kumar… - Insects, 2018 - mdpi.com
Mosquitoes live under the endless threat of infections from different kinds of pathogens such
as bacteria, parasites, and viruses. The mosquito defends itself by employing both physical …

Impact of simultaneous exposure to arboviruses on infection and transmission by Aedes aegypti mosquitoes

C Rückert, J Weger-Lucarelli, SM Garcia-Luna… - Nature …, 2017 - nature.com
The recent emergence of both chikungunya and Zika viruses in the Americas has
significantly expanded their distribution and has thus increased the possibility that …

Mosquito trilogy: microbiota, immunity and pathogens, and their implications for the control of disease transmission

P Gabrieli, S Caccia, I Varotto-Boccazzi… - Frontiers in …, 2021 - frontiersin.org
In mosquitoes, the interaction between the gut microbiota, the immune system, and the
pathogens that these insects transmit to humans and animals is regarded as a key …

A Review: Aedes-Borne Arboviral Infections, Controls and Wolbachia-Based Strategies

ST Ogunlade, MT Meehan, AI Adekunle, DP Rojas… - Vaccines, 2021 - mdpi.com
Arthropod-borne viruses (Arboviruses) continue to generate significant health and economic
burdens for people living in endemic regions. Of these viruses, some of the most important …

Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infection

WS Lee, JA Webster, ET Madzokere, EB Stephenson… - Parasites & vectors, 2019 - Springer
Mosquito-borne diseases are associated with major global health burdens. Aedes spp. and
Culex spp. are primarily responsible for the transmission of the most medically important …

RNA interference is essential to modulating the pathogenesis of mosquito-borne viruses in the yellow fever mosquito Aedes aegypti

GH Samuel, T Pohlenz, Y Dong… - Proceedings of the …, 2023 - National Acad Sciences
While it has long been known that the transmission of mosquito-borne viruses depends on
the establishment of persistent and nonlethal infections in the invertebrate host, specific …

Aedes aegypti Molecular Responses to Zika Virus: Modulation of Infection by the Toll and Jak/Stat Immune Pathways and Virus Host Factors

YI Angleró-Rodríguez, HJ MacLeod, S Kang… - Frontiers in …, 2017 - frontiersin.org
Zika (ZIKV) and dengue virus (DENV) are transmitted to humans by Aedes mosquitoes.
However, the molecular interactions between the vector and ZIKV remain largely …

Prevention and control strategies to counter dengue virus infection

IA Rather, HA Parray, JB Lone, WK Paek… - Frontiers in cellular …, 2017 - frontiersin.org
Dengue is currently the highest and rapidly spreading vector-borne viral disease, which can
lead to mortality in its severe form. The globally endemic dengue poses as a public health …

Subgenomic flaviviral RNAs: What do we know after the first decade of research

A Slonchak, AA Khromykh - Antiviral research, 2018 - Elsevier
The common feature of flaviviral infection is the accumulation of abundant virus-derived
noncoding RNA, named flaviviral subgenomic RNA (sfRNA) in infected cells. This RNA …