How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

The emergence of tissue form in multicellular organisms results from the complex interplay
between genetics and physics. In both plants and animals, cells must act in concert to …

Brillouin microscopy can assess mechanical properties of biological samples in a three-
dimensional (3D), all-optical and hence non-contact fashion, but its weak signals often lead …

Cell apical constriction driven by actomyosin contraction forces is a conserved mechanism
during tissue folding in embryo development. While much is now understood of the …

From a physical perspective, morphogenesis of tissues results from interplay between their
material properties and the mechanical forces exerted on them. The importance of …

Tissue morphogenesis occurs in a complex physicochemical microenvironment with limited
experimental accessibility. This often prevents a clear identification of the processes that …

As tissues grow and change shape during animal development, they physically pull and
push on each other, and these mechanical interactions can be important for morphogenesis …

Actin cortex patterning and dynamics are critical for cell shape changes. These dynamics
undergo transitions during development, often accompanying changes in collective cell …

During development, gene expression regulates cell mechanics and shape to sculpt tissues.
Epithelial folding proceeds through distinct cell shape changes that occur simultaneously in …

Cellular sorting and pattern formation are crucial for many biological processes such as
development, tissue regeneration, and cancer progression. Prominent physical driving …